| Copolymer 1 |
(Co
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| Copolymer 1 |
GA is a synthetic random copolymer of the four amino acids l-glutamic acid, l-lysine, l-alanine, and l-tyrosine (78?0). After clinical trials had shown benefit (81?6), GA was approved for the treatment of relapsing remitting MS. The beneficial effects of GA were subsequently confirmed by MRI studies (87). Compared with the MRI-confirmed effects of IFN-? those of GA are delayed (87). This delay appears to be consistent with the time course of the GA-induced immunological changes (88).
출처: www.pubmedcentral.nih.gov/articlerender.fcgi
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