| colistin | <chemical> Cyclic polypeptide antibiotic from bacillus colistinus. It is composed of polymyxins e1 and e2 (or colistins a, b, and c) which act as detergents on cell membranes. Colistin is less toxic than polymyxin b, but otherwise similar; the methanesulfonate is used orally. Pharmacological action: antibiotics, peptide. Chemical name: Colistin (12 Dec 1998) |
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| colistin sulfomethate sodium | Pentasodium colistinmethanesulfonate;contains the pentasodium salt of the penta(methanesulfonic acid) derivative of colistin A as the major component, with a small proportion of the pentasodium salt of the same derivative of colistin B; an effective antibiotic against most Gram-negative bacilli (except Proteus), given intramuscularly. See: colistin sulfate, polymyxin. Synonym: cholistine sulphomethate sodium, colistin sulfomethate sodium. (05 Mar 2000) |
| colistinase | <enzyme> Serine alkaline protease from bacillus polymyxa var. Colistinus Registry number: EC 3.4.21.- Synonym: colistinase I, colistinase II (26 Jun 1999) |