| CoA | <abbreviation> Coenzyme A. (05 Mar 2000) |
|---|---|
| CoA transferases | Thiaphorases;enzymes transferring CoA from acetyl-CoA or succinyl-CoA to other acyl radicals. (05 Mar 2000) |
| coacervate | <biology> Colloidal aggregation containing a mixture of organic compounds. One theory of the evolution of life is that the formation of coacervates in the primeval soup was a step towards the development of cells. (18 Nov 1997) |
| coacervation | Formation of a coacervate. (05 Mar 2000) |
| coadaptation | The operation of selection jointly on two or more loci. (05 Mar 2000) |
| coagglutination | Coagglutination is similar to the latex agglutination technique for detecting antigen (described above). Protein A, a uniformly distributed cell wall component of Staphylococcus aureus, is able to bind to the Fc region of most IgG isotype antibodies leaving the Fab region free to interact with antigens present in the applied specimens. The visible agglutination of the S. Aureus particles indicates the antigen-antibody reaction. (05 Mar 2000) |
| coagglutinin | A substance that per se does not agglutinate an antigen, but does result in agglutination of antigen that is appropriately coated with univalent antibody. See: conglutination. (05 Mar 2000) |
| coagula | Plural of coagulum. (05 Mar 2000) |
| coagulable | Capable of being coagulated or clotted. (05 Mar 2000) |
| coagulant | 1. An agent that causes, stimulates, or accelerates coagulation, especially with reference to blood. Synonym: coagulative. (05 Mar 2000) |
| coagulants | Exogenous substances used to promote blood coagulation. The endogenous blood coagulation factors are considered to be coagulants only when administered as drugs. (12 Dec 1998) |
| coagulase | Any bacterial component or product which causes coagulation in plasma containing an anticoagulant such as citrate, heparin or oxalate. Coagulases are produced by certain staphylococci and by yersinia pestis. Staphylococci produce two types of coagulase: staphylocoagulase, a free coagulase that produces true clotting of plasma, and staphylococcal clumping factor, a bound coagulase in the cell wall that induces clumping of cells in the presence of fibrinogen. (12 Dec 1998) |
| coagulate | 1. To convert a fluid or a substance in solution into a solid or gel. 2. To clot; to curdle; to change from a liquid to a solid or gel. Origin: L. Coagulo, pp. -atus, to curdle (05 Mar 2000) |
| coagulation | 1. <haematology> The process of clot formation. 2. <chemistry> The solidification of a sol into a gelatinous mass, an alteration of a disperse phase or of a dissolved solid which causes the separation of the system into a liquid phase and an insoluble mass called the clot or curd. Coagulation is usually irreversible. 3. <surgery> The disruption of tissue by physical means to form an amorphous residuum, as in electrocoagulation and photocoagulation. Origin: L. Coagulatio (18 Nov 1997) |
| coagulation factor | <haematology> Group of plasma protein substances (Factor I-XIII) contained in the plasma, which act in concert to bring about blood coagulation. Many of the factors contain EGF like domains. (29 Sep 1997) |
| butyryl-CoA acetoacetate CoA transferase | <enzyme> Butyryl-CoA + acetoacetate yields butyrate + acetoacetyl-CoA Registry number: EC 2.8.3.- Synonym: butyryl-coenzyme a acetoacetate coenzyme a transferase (26 Jun 1999) |
|---|---|
| malonyl-CoA-acetyl CoA-acyl carrier protein S-acyltransferase | <enzyme> Specific for either malonyl-CoA or acetyl-CoA; a component of fatty acid synthase Registry number: EC 2.8.3.- Synonym: mcoa-acoa acp acyltransferase (26 Jun 1999) |
| succinyl-CoA-3-hydroxy-3-methylglutarate CoA transferase | <enzyme> Rat liver mitochondrial enzyme which catalyses transfer of a conezyme a molecule from succinyl-CoA to 3-hydroxy-3-methylglutarate Registry number: EC 2.8.3.- Synonym: succinylcoa-hmg CoA transferase, sca-hmg cat (26 Jun 1999) |
| succinyl CoA propionate CoA-transferase | <enzyme> Succinyl CoA and propionate gives propionyl CoA and succinate Registry number: EC 2.8.3.- Synonym: succinyl coenzyme a propionate coenzyme a-transferase (26 Jun 1999) |
| enoyl-CoA hydratase - 3-hydroxyacyl-CoA dehydrogenase - dodecanoyl-coenzyme A delta-isomerase | <chemical> Catalyses the second and third reactions of the fatty acid beta-oxidation cycle, converting enoyl-CoA to 3-ketoacyl-CoA; EC 4.2.1.17 and EC 1.1.1.35 and EC 5.3.3.8; consider also multifunctional protein-a Synonym: peroxisomal bifunctional enzyme, enoyl-coenzyme a hydratase -- 3-hydroxyacyl-coenzyme a dehydrogenase, peroxisomal trifunctional enzyme, delta(3), delta(2)-enoyl-CoA isomerase--2-enoyl-CoA hydratase--3-hydroxyacyl-CoA dehydrogenase (26 Jun 1999) |
| acetate-CoA ligase | <enzyme> An enzyme that catalyses the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates. Chemical name: Acetate:CoA ligase (AMP-forming) Registry number: EC 6.2.1.1 (12 Dec 1998) |
| acetate-succinate CoA-transferase | <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA Registry number: EC 2.8.3.- Synonym: acetate-succinate coenzyme a-transferase (26 Jun 1999) |
| acetoacetyl-CoA | Intermediate in the oxidation of fatty acids and in the formation of ketone bodies; also formed from two molecules of acetyl-CoA; major role is condensation with acetyl-CoA to form the important beta-hydroxy-beta-methylglutaryl-CoA. Synonym: acetoacetyl-coenzyme A. (05 Mar 2000) |
| acetoacetyl-CoA reductase | An oxidoreductase catalyzing interconversion of a 3-oxoacyl-CoA and NADPH, and the corresponding d-3-hydroxyacyl-CoA, and NADP+. A step in fatty acid synthesis. (05 Mar 2000) |
| acetoacetyl-CoA synthetase | <enzyme> Catalyses the conversion of acetoacetate and CoA in the presence of ATP to yield AMP, pyrophosphate and acetoacetyl-CoA; the latter is the first intermediate in cholesterogenesis; also acts more slowly on l-3-hydroxybutanoate Registry number: EC 6.2.1.16 Synonym: acetoacetyl-CoA ligase, acetoacetate-CoA ligase, acetoacetyl-coenzyme a synthetase (26 Jun 1999) |
| acetoacetyl-CoA thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| acetyl-CoA | <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis. This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc. Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A. Synonym: acetyl-coenzyme A, active acetate. (05 Mar 2000) |
| acetyl-CoA-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase | <enzyme> Transfers acetate from acetyl CoA to the sn-2-position of 1-alkyl-2-lyso-glycerophosphocholine, forming the substrate for 1-alkylglycerophosphocholine acetyltransferase (EC 2.3.1.67) Registry number: EC 2.3.1.- Synonym: acopc acetyltransferase, 1-alkyl-2-lyso-sn-glycero-3-phosphocholine-acetyl CoA acetyltransferase, alkyllyso-gp-acetyl-CoA acetyltransferase, acetyl-coenzyme a-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase (26 Jun 1999) |
| acetyl-CoA acetyltransferase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| acetyl-CoA acylase | <enzyme> An enzyme that catalyses reversibly the hydrolysis of acetyl-CoA to yield CoA and acetate. The enzyme is involved in the oxidation of fatty acids. Chemical name: Acetyl-CoA hydrolase Registry number: EC 3.1.2.1 (12 Dec 1998) |