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wasting disease A graft versus host reaction in mice first observed following intravenous injection of allogeneic spleen cells into newborn animals.
Synonym: wasting disease.
(05 Mar 2000)
wasting Causing waste; also, undergoing waste; diminishing; as, a wasting disease; a wasting fortune.
<medicine> Wasting palsy, progressive muscular atrophy. See Progressive.
Source: Websters Dictionary
(01 Mar 1998)
wasting palsy A serious neurologic disease that results from the progressive degeneration of the motor neurons.
(27 Sep 1997)
wasting paralysis A serious neurologic disease that results from the progressive degeneration of the motor neurons.
(27 Sep 1997)
wasting syndrome <syndrome> A condition characterised by loss of ten percent of normal weight without obvious cause. The weight loss is largely the result of depletion of the protein in lean body mass and represents a metabolic derangement frequent during AIDS.
(31 Dec 1997)
salt wasting Inappropriately large renal excretion of salt despite the apparent need of the body to retain it.
(05 Mar 2000)
HIV wasting syndrome <syndrome> Involuntary weight loss of greater than 10 percent associated with intermittent or constant fever and chronic diarrhoea or fatigue for more than 30 days in the absence of a defined cause other than HIV infection. A constant feature is major muscle wasting with scattered myofibre degeneration. A variety of aetiologies, which vary among patients, contributes to this syndrome.
(12 Dec 1998)
anaemia of chronic disease <disease> A form of anaemia which develops as the result of a long-term infection or illness. Chronic diseases can interfere with red blood cell production in addition to shortening red blood cell life span in the body.
Symptoms are largely due to the underlying disease. Haemoglobin and haematocrit are generally low. Iron studies may be low to normal. Red blood cell indices may usually normal.
(27 Sep 1997)
granulomatous disease, chronic A recessive x-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation.
(12 Dec 1998)
chronic active liver disease Any of several types of hepatitis persisting for more than six months, often progressing to cirrhosis.
Synonym: chronic active liver disease.
(05 Mar 2000)
chronic disease Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care.
(12 Dec 1998)
chronic granulomatous disease <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase.
Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the cells are tested. The absence of the oxygen dependent killing mechanism is not itself fatal but seriously compromises the primary defense system.
at least three separate lesions can cause the syndrome, the commonest being a defect in plasma membrane cytochrome.
Acronym: CGD
(12 Jan 1998)
chronic granulomatous disease of childhood <radiology> Disorder of phagocytosis, two forms: X-linked recessive, autosomal recessive, usually fatal in childhood, infection by nonpathogenic organisms (catalase positive), pneumonia, osteomyelitis, diarrhoea, abdominal pain Findings: recurrent pneumonia (resolves incompletely, with abscess formation), adenopathy (big hila), hepatosplenomegaly, calcified granulomata in liver, spleen, lymph nodes, gastric antral narrowing (!) Cf: Chediak-Higashi syndrome More info: chronic granulomatous disease
(12 Dec 1998)
chronic hypertensive disease The chronic accumulative effects of long-standing high blood pressure on such vital organs as the heart, kidney, and brain.
(05 Mar 2000)
chronic obstructive pulmonary disease <disease> A progressive disease process that most commonly results from smoking. Chronic obstructive pulmonary disease is characterised by difficulty breathing, wheezing and a chronic cough.
Treatment includes absolute avoidance from smoking, bronchodilators and oxygen for those with advanced disease. Complications include bronchitis, pneumonia and lung cancer.
See: emphysema.
(27 Sep 1997)
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