| acute nephritic syndrome | <nephrology, syndrome> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood). Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis). (15 Jan 1998) |
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| nephritic syndrome | <syndrome> A disease of the kidneys that results in inflammation of the glomerulus (the portion of the kidney that filters the blood). Conditions which may cause glomerulonephritis include post-streptococcal disease (strep throat), lupus, syphilis, bacterial endocarditis, membranoproliferative glomerulonephritis, sepsis, vasculitis, Goodpasture's syndrome, typhoid fever, Henoch-Schonlein purpura, hepatitis or a viral infection (for example mumps, measles, mononucleosis). (27 Sep 1997) |
| complement 3 nephritic factor | A magnesium-dependent IgG autoantibody found in serum of patients with chronic mesangioproliferative hypocomplementemic glomerulonephritis. It causes inactivation of c3 in the alternate pathway by cleaving c3 into two inactive fragments, c3c and c3d, instead of the normal c3b. (12 Dec 1998) |
| nephritic | <medicine> A medicine adapted to relieve or cure disease of the kidneys. Source: Websters Dictionary (01 Mar 1998) |
| nephritic calculus | An obsolete term for renal calculus. (05 Mar 2000) |
| nephritic factor | A serum protein (possibly an IgG autoantibody), found in some patients with membranoproliferative glomerulonephritis and hypocomplementemia, which, together with the cofactors of the alternate pathway of complement activation, cleaves the third component of complement (C3). (05 Mar 2000) |
| chronic fatigue syndrome | <syndrome> An unusual illness, of uncertain cause, that is characterised by unexplained fatigue, weakness, muscle pain, lymph node swelling and malaise. (27 Sep 1997) |
| chronic hyperventilation syndrome | <syndrome> Reduced CO2 content of the blood (hypocapnia) as a result of hyperventilation of prolonged duration; may occur in anxiety states and in some chronic organic, usually cardiovascular, disease; alkalaemia, paresthesia, and tetany may occur. (05 Mar 2000) |
| fatigue syndrome, chronic | Syndrome of unknown cause, characterised by clinically evaluated, unexplained persistent or relapsing chronic fatigue of at least six months' duration which is not the result of ongoing exertion; is not substantially alleviated by rest; and results in substantial reduction of previous levels of occupational, educational, social, or personal activities. Common concurrent symptoms (of six months duration) include impairment of memory or concentration, diffuse pain, sore throat, tender lymph nodes, headaches of a new type, pattern, or severity, and unrefreshing sleep. The aetiology is suspected to be viral or immunologic. There are suggestions that chronic fatigue syndrome (sometimes called myalgic encephalomyelitis) may be identical to neurasthenia and fibromyalgia. (12 Dec 1998) |
| anaemia of chronic disease | <disease> A form of anaemia which develops as the result of a long-term infection or illness. Chronic diseases can interfere with red blood cell production in addition to shortening red blood cell life span in the body. Symptoms are largely due to the underlying disease. Haemoglobin and haematocrit are generally low. Iron studies may be low to normal. Red blood cell indices may usually normal. (27 Sep 1997) |
| benign familial chronic pemphigus | Recurrent eruption of vesicles and bullae that become scaling and crusted lesions with vesicular borders, predominantly of the neck, groin, and axillary regions; autosomal dominant inheritance, presenting in late adolescence or early adult life. Synonym: Hailey-Hailey disease. (05 Mar 2000) |
| candidiasis, chronic mucocutaneous | A clinical syndrome characterised by development, usually in infancy or childhood, of a chronic, often widespread candidiasis of skin, nails, and mucous membranes. It may be secondary to one of the immunodeficiency syndromes, inherited as an autosomal recessive trait, or associated with defects in cell-mediated immunity, endocrine disorders, dental stomatitis, or malignancy. (12 Dec 1998) |
| granulomatous disease, chronic | A recessive x-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. (12 Dec 1998) |
| persistent chronic hepatitis | A benign chronic hepatitis that may follow acute viral hepatitis A or B, or complicate bowel diseases; after six months, liver biopsy changes are mild, unlike active chronic hepatitis; rarely, if ever, progresses to cirrhosis, portal hypertension, or liver failure. (05 Mar 2000) |
| chronic | Persisting over a long period of time. Origin: L. Chronicus, Gr. Chronos = time (18 Nov 1997) |