| cholestyramine | <chemical> Strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium as cl(-) anion. It exchanges chloride ions with bile salts, thus decreasing their concentration and that of cholesterol. It is used as a hypocholesteraemic in diarrhoea and biliary obstruction and as an antipruritic. Pharmacological action: anion exchange resins, anticholesteraemic agents, antipruritics. Chemical name: Cholestyramine (12 Dec 1998) |
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| cholestyramine resin | A strongly basic anion-exchange resin in the chloride form, consisting of a copolymer of styrene and divinylbenzene with quaternary ammonium functional groups; it lowers the blood cholesterol by binding the bile acids in the intestine, thus promoting their excretion in the faeces instead of reabsorption from the bowel; used in the treatment of hypercholesterolaemia, xanthomatous biliary cirrhosis, and other forms of xanthomatosis. (05 Mar 2000) |