Chloramphenicol : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 3 페이지: 1

Chloramphenicol - 새창 An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)
Synonyms : Chlornitromycin, Chlorocid, Chloromycetin, Detreomycin, Ophthochlor, Syntomycin
Chloramphenicol O-Acetyltransferase - 새창 An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
Synonyms : Chloramphenicol Transacetylase, Acetyltransferase, Chloramphenicol, Chloramphenicol O Acetyltransferase, Enzyme, CAT, O-Acetyltransferase, Chloramphenicol, Transacetylase, Chloramphenicol
Chloramphenicol Resistance - 새창 Nonsusceptibility of bacteria to the action of CHLORAMPHENICOL, a potent inhibitor of protein synthesis in the 50S ribosomal subunit where amino acids are added to nascent bacterial polypeptides.
Synonyms : Chloramphenicol Resistances