| Castle's intrinsic factor | A mucoprotein normally secreted by the epithelium of the stomach and that binds vitamin B12, the intrinsic factor/B12 complex is selectively absorbed by the distal ileum, though only the vitamin is taken into the cell. (18 Nov 1997) |
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| Castle, William | <person> U.S. Physician, *1897. See: Castle's intrinsic factor. (05 Mar 2000) |
| castleman disease | <radiology> Angiofollicular lymph node hyperplasia, benign lymphoid hyperplasia, massively enlarged lymph nodes, mediastinum most common; rarely in mesentery, age less than 30 yrs, types: hyaline vascular (90%), asymptomatic, vascular proliferation and hyalinization, plasma cell (10%), fever, anaemia, increased sed rate, increased IgG (12 Dec 1998) |
| Castleman's disease | Solitary masses of lymphoid tissue containing concentric perivascular aggregates of lymphocytes, occurring usually in the mediastinum or hilar region of young adults; similar changes have been reported outside the mediastinum and, if associated with interfollicular sheets of plasma cells, may progress to lymphoma or plasmacytoma. Synonym: angiofollicular mediastinal lymph node hyperplasia, Castleman's disease. (05 Mar 2000) |
| Castleman, Benjamin | <person> U.S. Pathologist, 1906-1982. See: Castleman's disease. (05 Mar 2000) |