| gene products, rev | Trans-acting nuclear proteins whose functional expression are required for HIV viral replication. Specifically, the rev gene products are required for processing and translation of the HIV gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. Rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (car) in env, also known as the rev-responsive element (rre), is responsive to the rev gene product. Rev is short for regulator of virion. (12 Dec 1998) |
|---|---|
| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| rev | <molecular biology> A regulatory protein produced by HIV within infected cells. Rev helps transport HIV RNA sequences (messenger RNA) out from the nucleus into the cells cytoplasm, where it directs construction of proteins for new virus particles. (11 Jan 1998) |
| biochemical metastasis | The transportation and induction of abnormal immunochemical specificities in apparently normal organs. (05 Mar 2000) |
| calcareous metastasis | The deposit of calcareous material in remote tissues in the event of extensive resorption of osseous tissue in caries, malignant neoplasms, and so on. (05 Mar 2000) |
| metastasis | 1. <cell biology, oncology> The transfer of disease from one organ or part to another not directly connected with it. It may be due either to the transfer of pathogenic microorganisms (for example, tubercle bacilli) or to transfer of cells, as in malignant tumours. The capacity to metastasize is a characteristic of all malignant tumours. 2. Pleural: metastases. A growth of pathogenic microorganisms or of abnormal cells distant from the site primarily involved by the morbid process. Origin: Gr. Stasis = stand, stoppage (12 Nov 1997) |
| haematogenous metastasis | See: metastasis. (05 Mar 2000) |
| satellite metastasis | Metastasis within the immediate vicinity of a primary malignant neoplasm; e.g., skin adjacent to a melanoma. (05 Mar 2000) |
| neoplasm metastasis | The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. The ability to metastasize is characteristic of all malignant neoplasms. (12 Dec 1998) |
| lymphatic metastasis | Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (12 Dec 1998) |
| lymphogenous metastasis | See: metastasis. (05 Mar 2000) |
| American Cancer Society | <address, organisation> American Cancer Society, National Headquarters, 1599 Clifton Road, NE, Atlanta, GA 30329 USA. Tel: 00 1 404 320-3333 (05 Feb 1998) |
| bladder cancer | The most common warning sign of bladder cancer is blood in the urine. The diagnosis of bladder cancer is supported by findings in the medical history and examination, blood, urine, and X-ray tests, and confirmed with a biopsy (usually during a cystoscope exam). Treatment of bladder cancer depends on the growth, size, and location of the tumour. (12 Dec 1998) |
| bladder cancer risks | Smoking is a major risk factor. Cigarette smokers develop bladder cancer 2-3 times more often than do nonsmokers. Quitting smoking reduces the risk of bladder cancer, lung cancer, several other types of cancer, and a number of other diseases as well. Workers in some occupations are at higher risk of developing bladder cancer because of exposure to carcinogens (cancer-causing substances) in the workplace. These workers include people in the rubber, chemical, and leather industries, as well as hairstylists, machinists, metal workers, printers, painters, textile workers, and truck drivers. (12 Dec 1998) |
| bone cancer | <oncology> A general term to imply malignant tumour growth in bone. (27 Sep 1997) |