| CSF | 1. Colony-stimulating factor. 2. Cerebrospinal fluid. (06 Aug 1998) |
|---|---|
| CSF leak | <neurology> The leak of cerebrospinal fluid from the cavities within the brain (ventricles) or the spinal cord. CSF leak is a recognised complication of lumbar puncture. CSF leaks may also be seen after trauma to the head (for example CSF rhinorrhoea, CSF otorrhoea). (06 Aug 1998) |
| CSF rhinorrhoea | <orthopaedics> The leakage of a clear fluid out the nose. May be seen in cases of basilar skull fracture. (06 Aug 1998) |
| G-CSF | <growth factor, haematology, oncology> A glycoprotein of 25 kD containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukaemic myeloid cell lines. A protein that stimulates the growth and maturation of granulocytes. It is used to promote the recovery of the white cells following chemotherapy. See: colony-stimulating factor. Acronym: G-CSF (12 Dec 1998) |
|---|---|
| M-CSF | macrophage-colony-stimulating factor |
| GM-CSF | <growth factor, haematology, oncology> An acidic glycoprotein of mw 23 kD with internal disulfide bonds. It is produced in response to a number of inflammatory mediators by mesenchymal cells present in the haemopoietic environment and at peripheral sites of inflammation. It stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from foetal liver progenitor cells. It also has some functional activities in mature granulocytes and macrophages. It is used to promote the recovery of the white blood cells following chemotherapy. Chemical name: Colony-stimulating factor 2 See: colony-stimulating factor. Acronym: GM-CSF (12 Dec 1998) |
| multi-CSF | <abbreviation> Multi-colony-stimulating factor. (05 Mar 2000) |