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cafe-au-lait spot <dermatology> A pigmented cutaneous lesion, that can range from light to dark brown, and is due to an excess of melanosomes in the malpighian cells, rather than to an excess of melanocytes.
Caf
caffearine N-methylnicotinic acid;the methyl betaine of nicotinic acid; a product of the metabolism of nicotinic acid; excreted in the urine.
Synonym: caffearine, trigenolline.
(05 Mar 2000)
caffeate O-methyltransferase <enzyme> Caffeic acid methylated to ferulic acid; a separate enzyme (EC 2.1.1.104) acts on caffeoyl-CoA; jrg5 isolated from barley
Registry number: EC 2.1.1.68
Synonym: sam-ca-methyltransferase, s-adenosylmethionine caffeic acid o-methyltransferase, caffeic acid o-methyltransferase, 5-hydroxyferulic acid o-methyltransferase, bispecific o-methyltransferase, lignin o-methyltransferase, caffeic acid 3-o-methyltransferase, caomt protein, jrg5 gene product, omt1 protein
(26 Jun 1999)
caffeate peroxidase <enzyme> Catalyses dimerization of ferulic acid or caffeic acid via oxidative coupling and formation of beta,beta-linkage to lignan-type cpds 8,8'-bis(caffeic acid) or 8,8'-bis(ferulic acid)
Registry number: EC 1.11.1.-
(26 Jun 1999)
caffeic acids 3,4-dihydroxycinnamic acids. A class of phenolic acids related to chlorogenic acid,p-coumaric acid, vanillic acid, etc., which are found in plant tissues. It is involved in plant growth regulation.
(12 Dec 1998)
caffeine <chemical> A xanthine derivative that elevates cAMP levels in cells by inhibiting phosphodiesterases.
(18 Nov 1997)
caffeine and sodium benzoate A mixture of equal parts of sodium benzoate and caffeine, used to meet the indication of caffeine.
(05 Mar 2000)
caffeine and sodium salicylate A mixture of sodium salicylate and caffeine used for the relief of headache and neuralgia.
(05 Mar 2000)
caffeine citrate Citrated caffeine, a mixture of equal parts of caffeine and citric acid.
(05 Mar 2000)
caffeine hydrate Monohydrate of caffeine, a central nervous system stimulant.
(05 Mar 2000)
caffeinism Caffeine intoxication characterised by restlessness, tremulousness, nervousness, excitement, insomnia, flushed face, diuresis, and gastrointestinal complaints, brought on by the ingestion of substances containing caffeine.
(05 Mar 2000)
caffeoyl-CoA O-methyltransferase <enzyme> Catalyses the methylation of caffeoyl-CoA to form trans-feruloyl-CoA; also accepts with low affinity various other caffeic esters as substrates; do not confuse with EC 2.1.1.68 which acts on caffeic acid; has been sequenced; genbank l22203 (stellaria longipes)
Registry number: EC 2.1.1.104
Synonym: sam-c-CoA 3-o-methyltransferase, s-adenosylmethionin-trans-caffeoyl-coenzyme a 3-o-methyltransferase, sam-cca-methyltransferase, caffeoyl-CoA-3-o-methyltransferase, s-adenosyl-l-methionine-trans-caffeoyl-coenzyme a 3-o-methyltransferase, ccoaomt, s-adenosylmethionine-trans-caffeoyl-CoA 3-o-methyltransferase, ccoamt
(26 Jun 1999)
caffey disease <radiology> Infantile cortical hyperostosis, aetiology unknown, onset before 5 months of age, hyperostosis and periosteal reaction, mandible (80-95%), clavicles, ribs, long bones (DIAPHYSES often asymmetric) Differential diagnosis: if metaphyses involved, consider battery (child abuse)
(12 Dec 1998)
Caffey's disease Neonatal subperiosteal bone formation over many bones, especially the mandible and clavicles and the shafts of long bones; it follows fever, usually appearing before 6 months of age and disappearing during childhood.
Synonym: Caffey's disease, Caffey's syndrome, Caffey-Silverman syndrome.
(05 Mar 2000)
Caffey's syndrome Neonatal subperiosteal bone formation over many bones, especially the mandible and clavicles and the shafts of long bones; it follows fever, usually appearing before 6 months of age and disappearing during childhood.
Synonym: Caffey's disease, Caffey's syndrome, Caffey-Silverman syndrome.
(05 Mar 2000)
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