| C4b |
a constituent of the classical pathway C3 convertase (C4b,2a), generated by cleavage of C4 by C1s; the active fragment C4b then binds C2 for cleavage of C2 by C1s. It is inactivated by factor I in the presence of C4 binding protein. C4b is also an opsonin that binds to the same receptors as C3b.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| C4b,2a |
the classical pathway C3 convertase, which cleaves C3 to C3a and C3b, a complex of C4b and C2a formed on cell membrane surfaces in the presence of Mg2+. See also notes at C2a and complement.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| C4b,2a,3b |
the classical pathway C5 convertase, which cleaves C5 to C5a and C5b; the complex is formed by attachment of C3b to membrane-bound C4b,2a. See also notes at C2a and complement.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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