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peripheral blood stem cell transplantation A procedure that is similar to bone marrow transplantation. Doctors remove healthy immature cells (stem cells) from a patient's blood and store them before the patient receives high-dose chemotherapy and possibly radiation therapy to destroy the leukaemia cells. The stem cells are then returned to the patient, where they can produce new blood cells to replace cells destroyed by the treatment.
(12 Dec 1998)
cell transplantation Transference of cells within an individual, between individuals of the same species, or between individuals of different species.
(12 Dec 1998)
haematopoietic stem cell transplantation The transference of stem cells from one animal or human to another (allogeneic), or within the same individual (autologous). The source for the stem cells may be the bone marrow or peripheral blood. Stem cell transplantation has been used as an alternative to autologous bone marrow transplantation in the treatment of a variety of neoplasms.
(12 Dec 1998)
blood cell <haematology> There are three main types of cell in the blood stream.
The red cell, which carries oxygen, the white cell, which fights infections and the platelet, which helps prevent bleeding. The correct balance between each cell type must be maintained for the body to remain healthy.
(13 Nov 1997)
blood cell count A count of the number of leukocytes and erythrocytes per unit volume in a sample of venous blood. A complete blood count (cbc) also includes measurement of the haemoglobin, haematocrit, and erythrocyte indices.
(12 Dec 1998)
packed red blood cell <haematology> Red blood cells collected from one individual that are packed into a small volume for transfusion into a patient.
(16 Dec 1997)
red blood cell <haematology> Cell specialised for oxygen transport, having a high concentration of haemoglobin in the cytoplasm (and little else). Biconcave, anucleate discs, 7nm diameter in mammals, nucleus contracted and chromatin condensed in other vertebrates.
Acronym: RBC
(18 Nov 1997)
red blood cell cast A urinary cast composed of a matrix containing red cells in various stages of degeneration and visibility, characteristic of glomerular disease or renal parenchymal bleeding.
Synonym: red cell cast.
(05 Mar 2000)
red blood cell count A normal value is 4.6-6.2 million RBC's per cubic millimetre of blood. This number can increase in cases of dehydration (fluid loss) or severe lung disease. Interestingly, red blood cell counts are much higher in those who live at high altitude, because of the increased demand for oxygen carrying capacity.
(27 Sep 1997)
red blood cell indices Laboratory measurements of red blood cell volume, size and haemoglobin concentration. These values are used to point to the specific cause for anaemia (iron deficiency, B12 deficiency, etc.)
(27 Sep 1997)
white blood cell <haematology> White corpuscles in the blood. They are spherical, colourless and nucleated masses involved with host defenses.
Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. Elevated counts can be seen in cases of inflammation and infection.
See: leucocytes, basophils, coelomocytes, eosinophils, haemocytes, lymphocytes, neutrophils, monocytes.
Acronym: WBC
(13 Nov 1997)
white blood cell cast A urinary cast composed of polymorphonuclear leukocytes, characteristic of tubulointerstitial disease, especially pyelonephritis.
(05 Mar 2000)
white blood cell count <haematology> A laboratory test which measures the number of white blood cells per cubic millimetre of blood.
Normal white blood cell counts are variable with age and sex. Normal adult range is 4, 500 to 11,000 cells per cubic millimetre of blood. Slightly higher counts are seen in children. Elevated counts can be seen in cases of inflammation and infection.
(13 Nov 1997)
white blood cell differential <haematology> The white blood cell differential is a percentage of each type of white blood cell based on a count of 100 white cells.
A change in the white blood cell type (to neutrophils or bands) can indicate a bacterial infection. Neutrophils, bands, lymphocytes, monocytes, basophils and eosinophils are all included.
(13 Nov 1997)
bone marrow transplantation <oncology, procedure> Treatment in which healthy bone marrow replaces bone marrow that has been affected by a disease or by treatment for a disease.
Acronym: BMT
(12 May 1997)
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