| HLA-b27 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the b locus on chromosome 6. It is strongly associated with acute anterior uveitis, ankylosing spondylitis, and reiter's disease. Increased frequency of antigen in: ankylosing spondylitis (90%), Reiter syndrome (90%), enteropathic arthritis (75%), psoriatic arthritis (60%) normal frequency: white: 8%, black: 4% (12 Dec 1998) |
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