| atropine | <drug> A toxic alkaloid extracted from belladonna and other members of thenightshade family, it is typically used to dilate the eye and to stopmuscular spasms. Pharmacologic action: Parasympatholytic. Competitive blockade of acetylcholine at muscarinic receptors. Increases sinus node automaticity and AV conduction. Uses: Treat bradycardia, asystole, and AV block Dose: 0.5 - 1.0 mg for bradycardia every 3 - 5 min to a total dose of 0.04 mg/kg. Doses smaller than 0.5 mg can cause a paradoxical bradycardia due to sympathomimetic effects Typically 3 mg is adequate to completely block vagal effects Atropine is well absorbed via endotracheal route - administer 1-2 mg diluted in 10 mL sterile water or normal saline. Potential complications: 1. Tachyarrhythmias 2. Exacerbation of myocardial ischemia 3. Low dose may cause paradoxical bradycardia 4. Dry mouth, urinary retention, flushed and hot skin 5. Crosses blood-brain barrier which can cause delirium Note: The denervated heart will not respond to atropine. (15 Mar 2000) |
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| atropine dehydrase | <enzyme> Proposed mechanism for conversion of atropine or scopolamine to apoatropine or aposcopolamine via a mechanism using hydroxysteroid sulfotransferase by guinea pig liver Registry number: EC 2.8.2.- Synonym: scopolamine dehydrase (26 Jun 1999) |
| atropine derivatives | Analogs and derivatives of atropine. (12 Dec 1998) |
| atropine methonitrate | The methylnitrate of atropine, with the same actions and uses as atropine, but less lipid-soluble and hence with fewer central nervous system effects; a quaternary compound. (05 Mar 2000) |
| atropine methylbromide | A quaternary derivative of atropine that is less lipid soluble and hence produces fewer central nervous system actions; a cycloplegic. Synonym: atropine methylbromide. (05 Mar 2000) |
| atropine sulfate | An anticholinergic; a widely used soluble salt of atropine. (05 Mar 2000) |
| atropine test | If an injection of atropine relieves bradycardia, the condition is due to action of the vagus; if it does not, the condition may be due to an affection of the heart itself. Synonym: atropine test. (05 Mar 2000) |
| administration, oral | The giving of drugs, chemicals, or other substances by mouth. (12 Dec 1998) |
| cancer, oral | Cancer of the mouth area. A sore in the mouth that does not heal can be a warning sign of oral cancer. A biopsy is the only to know whether as abnormal area in the oral cavity is cancer. Oral cancer is caused by tobacco (smoking and chewing) and alcohol use. Surgery to remove the tumour in the mouth is the usual treatment for patients with oral cancer. (12 Dec 1998) |
| candidiasis, oral | Infection of the mucous membranes of the mouth by a fungus of the genus candida. (12 Dec 1998) |
| canine oral papilloma | Warts affecting mucous membranes of young dogs; caused by a papillomavirus. (05 Mar 2000) |
| magnesia and alumina oral suspension | A mixture of magnesium hydroxide and variable amounts of aluminum oxide; used as an antacid. (05 Mar 2000) |
| pathology, oral | A dental specialty concerned with pathology of the oral cavity. (12 Dec 1998) |
| pharyngo-oral | Relating to the pharynx and the mouth; oropharyngeal. Origin: pharyngo-+ L. Os (or-), mouth (05 Mar 2000) |
| combination oral contraceptive | A mixture of a steroid having progestational activity and an oestrogen. (05 Mar 2000) |