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AS Antisense
S Antisense
As-ODN Antisense oligodeoxynucleotide
AS-ODN Antisense oligonucleotide
ASO Antisense oligonucleotide
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  • JrId: 2169
    JournalTitle: Antisense research and development.
    MedAbbr: Antisense Res Dev
    ISSN: 1050-5261
    ESSN:
    IsoAbbr: Antisense Res. Dev.
    NlmId: 9110698
  • JrId: 20345
    JournalTitle: Antisense & nucleic acid drug development.
    MedAbbr: Antisense Nucleic Acid Drug Dev
    ISSN: 1087-2906
    ESSN:
    IsoAbbr: Antisense Nucleic Acid Drug Dev.
    NlmId: 9606142
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antisense <molecular biology> In general the complementary strand of a coding sequence of DNA (antisense DNA) or of mRNA (antisense RNA).
A collection of nucleotide sequences which are not templates for synthesis but yet interact with complementary sequences in other molecules thereby causing function of those molecules to be affected.
Antisense RNA hybridises with and inactivates mRNA.
(12 Dec 1998)
antisense DNA <molecular biology> A synthetic DNA strand that is complementary to a particular strand of target DNA with a complementary sequence of bases. This results in preventing expression of the gene encoded.
These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells.
(14 Nov 1997)
antisense RNA <molecular biology> A complementary RNA sequence that binds to (and thus blocks the transcription of) a naturally-occuring (sense) messenger RNA molecule.
These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells.
(09 Oct 1997)
antisense strand <molecular biology> The strand of DNA which is not used during transcription to make mRNA (anticoding strand). The mRNA made during transcription thus has the same sequence as this strand, so that the eventual protein will be a sense version.
(13 Jan 1998)
antisense therapy Use of antisense DNA for the inhibition of translation of a specific gene product for therapeutic purposes.
(05 Mar 2000)
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RNA, antisense An RNA molecule which, by binding to a complementary sequence in either RNA or DNA, inhibits the function and/or completion of synthesis of the latter molecule. It is involved in various regulatory systems in vivo. Artificial antisense rnas have been used to inhibit translation of specific mRNA molecules both in living cells (eukaryotic and bacterial) and in cell-free systems.
(12 Dec 1998)
DNA, antisense A DNA molecule which is complementary to the sense strand (that which functions as a template for the synthesis of mRNA) but is not involved in transcription. Both strands are involved in replication.
(12 Dec 1998)
oligonucleotides, antisense Short fragments (usually between 2 and 12 nucleotides) of DNA or RNA that are used to hinder or block the translation or processing of mRNA.
(12 Dec 1998)
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  • Antisense Elements (Genetics) - »õâ Nucleic acids which hybridize to complementary sequences in other target nucleic acids causing the function of the latter to be affected.
    Synonyms : Anti-Sense Elements, Anti-Sense Probes, Anti Sense Elements, Anti Sense Probes, Elements, Anti-Sense, Probes, Anti-Sense, Probes, Antisense
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antisense RNA an RNA molecule transcribed off the coding, rather than the template, strand of DNA, so that it is complementary to the sense (messenger) RNA; formation of a duplex between the sense and antisense RNA molecules blocks transcription and also subjects both molecules to double strand
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
antisense strand the strand of a double-stranded nucleic acid that is complementary to the sense strand, in DNA being thus the template strand on which the mRNA is synthesized. Cf. sense s. See also antisense RNA.
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
antisense RNA RNA product of mic (mRNA-interfering complementary RNA) genes that regulates another gene by base pairing with and thus preventing translation from its mRNA.
Ãâó: helios.bto.ed.ac.uk/bto/glossary/ab.htm
antisense a complementary piece of genetic material (DNA or RNA) that binds to another piece of DNA or RNA by base-pairing, which prevents that DNA/RNA fragment from being used to synthesize new proteins.
Ãâó: www.aegis.com/pubs/beta/1999/BE991221.html
antisense RNA RNA complementary to messenger RNA. When combined with messenger RNA, translation of the latter is blocked.
Ãâó: www.genethon.fr/php/layout.php
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