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fluorescein angiography <procedure> The process of taking X-rays of blood vessels that have been injected with a special dye. The dye allows to person viewing the X-ray to see the blood vessels.
(13 Nov 1997)
fluorescein <chemical> Fluorophore commonly used in microscopy.
Fluorescein di acetate can be used as a vital stain or can be conjugated to proteins (particularly antibodies) using isothiocyanate.
Excitation is at 365nm and the emitted light is green yellow (450-490nm). The emission spectrum is pH sensitive and fluorescein can therefore be used to measure pH in intracellular compartments.
(18 Nov 1997)
fluorescein-5-isothiocyanate <chemical> 3',6'-dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3h),9'-(9h)xanthen)-3-one. Fluorescent probe capable of being conjugated to tissue and proteins. It is used as a label in fluorescent antibody staining procedures as well as protein- and amino acid-binding techniques.
Pharmacological action: fluorescent dyes.
Chemical name: Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-
(12 Dec 1998)
fluorescein-conjugated antibody Refers to an antibody that has joined with a fluorescein molecule.
(09 Oct 1997)
fluorescein eye examination A special test that allows the examiner to detect cornea abrasions or corneal foreign bodies. An orange dye (fluorescein) is placed into the eye and the eye is illuminated with a cobalt blue light (black light). This serves to highlight any irregularities in the corneal surface.
(27 Sep 1997)
fluorescein instillation test A test for patency of the lacrimal system; fluorescein instilled in the conjunctival sac can be recovered from the inferior nasal meatus.
Synonym: Jones' test.
(05 Mar 2000)
fluorescein isothiocyanate <chemical> A fluorescent chemical derived from fluorescein which is used to label proteins.
(25 Jun 1999)
fluorescein sodium A dye used for diagnosis of certain ocular diseases, differentiation or delineation of organ parts in surgery, and determination of circulation time.
Synonym: resorcinolphthalein sodium, uranin.
(05 Mar 2000)
fluorescein string test A string test used to determine location of a bleeding intestinal lesion in which fluorescein is given intravenously to determine gastrointestinal haemorrhage; if the string fluoresces after removal, it has been contaminated by blood that has appeared since injection of the fluorescein; used to determine location of bleeding lesion.
(05 Mar 2000)
3-O-methyl-fluorescein phosphatase <enzyme> Used for assay of na-k-atpase in intact tissues
Registry number: EC 3.6.1.-
Synonym: 3-o-methylfluorescein phosphatase
(26 Jun 1999)
adrenal angiography <radiology> Adrenal arteriography, 3 arteries: superior - inferior phrenic a., middle - aorta, inferior - renal a., difficult to inject all 3; arteriography usually not attempted adrenal venography, venous sampling, may define anatomy, may rupture capsule and ablate function
(12 Dec 1998)
angiography <investigation> A radiographic technique where a radio-opaque (shows up on X-ray) contrast material is injected into a blood vessel for the purpose of identifying its anatomy on X-ray. This technique is used to image arteries in the brain, heart, kidneys, gastrointestinal tract, aorta, neck (carotids), chest, limbs and pulmonary circuit.
(27 Sep 1997)
angiography catheter A thin-walled tube suitable for percutaneous puncture and powered injection of contrast media for radiography; catheter diameter is measured on the French scale.
(05 Mar 2000)
angiography, digital subtraction A method of delineating blood vessels by subtracting a tissue background image from an image of tissue plus intravascular contrast material that attenuates the X-ray photons. The background image is determined from a digitised image taken a few moments before injection of the contrast material. The resulting angiogram is a high-contrast image of the vessel. This subtraction technique allows extraction of a high-intensity signal from the superimposed background information. The image is thus the result of the differential absorption of X-rays by different tissues.
(12 Dec 1998)
biplane angiography Synchronous angiocardiography in two planes at right angles to each other or in two orthogonal planes.
(05 Mar 2000)
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