| androgen resistance syndromes | A class of disorders associated with 5a-steroid reductase deficiency, testicular feminization, and related disorders. Compare: steroid 5a-reductase, Reifenstein's syndrome, infertile male syndrome, testicular feminization syndrome. (05 Mar 2000) |
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| adrenal androgen | Any androgenic hormone of adrenocortical origin; e.g., dehydroepiandrosterone (and its sulfate), androstenedione, 11b-hydroxyandrostenedione. (05 Mar 2000) |
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| adrenal androgen-stimulating hormone | A putative pituitary hormone that may be responsible for increased secretion of adrenal androgens at the time of puberty. (05 Mar 2000) |
| androgen | <endocrinology> General term for any male sex hormone in vertebrates. Androgens may be used in patients with breast cancer to treat recurrence of the disease. (14 May 1997) |
| androgen antagonists | Compounds which inhibit or antagonise the biosynthesis or actions of androgens. (12 Dec 1998) |
| androgen binding protein | A protein secreted by testicular Sertoli cells along with inhibin and mullerian inhibiting substance. Androgen binding protein probably maintains a high concentration of androgen in the seminiferous tubules. (05 Mar 2000) |
| androgen-binding proteins | Carrier proteins produced in the sertoli cells of the testis, secreted into the seminiferous tubules, and transported via the efferent ducts to the epididymis. Participate in the transport of androgens; include also synthetic androgens binding proteins. (12 Dec 1998) |
| androgen-dependent secretory protease | <enzyme> Glycoprotein from dog prostate; hydrolyzes arginine and lysine-containing amide and ester protease substrates Registry number: EC 3.4.99.- Synonym: ads-protease (26 Jun 1999) |
| androgen unit | The androgenic activity of 100 ug (0.1 mg) of crystalline androsterone as assayed by the comb growth response in capons. (05 Mar 2000) |
| receptors, androgen | Proteins, generally found in the cytoplasm, that specifically bind androgens and mediate their cellular actions. The complex of the androgen and receptor migrates to the nucleus where it induces transcription of specific segments of DNA. (12 Dec 1998) |
| thyroid hormone resistance syndrome | <syndrome> An inherited syndrome of peripheral resistance to thyroid hormones, transmitted as an autosomal recessive trait, characterised by increased serum concentrations of thyroxine and triiodothyronine, increased thyroid hormone binding ratio, and normal to slightly increased thyroid-stimulating hormone and its response to thyrotropin-releasing hormone. The affected persons are euthyroid to slightly hypothyroid. The absence of hypermetabolism and the presence of possible hypothyroidism indicate the existence of partial resistance to the peripheral action of thyroid hormone. (12 Dec 1998) |
| airway resistance | The opposition of the tracheobronchial tree to air flow: the mouth-to-alveoli pressure difference divided by the air flow. (12 Dec 1998) |
| ampicillin resistance | Nonsusceptibility of a microbe to the action of ampicillin, a penicillin derivative that interferes with cell wall synthesis. (12 Dec 1998) |
| antibiotic resistance | The ability of a bacterium tosynthesise a protein that neutralises an antibiotic. (09 Oct 1997) |
| antibiotic resistance gene | Genes in a microorganism which confer resistance to antibiotics, for example by coding for enzymes which destroy it, by coding for surface proteins which prevent it from entering the microorganism, or by being a mutant form of the antibiotic's target so that it can ignore it. (09 Oct 1997) |
| bacteriophage resistance | Resistance of a bacterial mutant to infection by a bacteriophage to which the parent (wild type) strain is susceptible. (05 Mar 2000) |