| sulbactam | <chemical> 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide. A beta-lactamase inhibitor with very weak antibacterial action. The compound prevents antibiotic destruction of beta-lactam antibiotics by inhibiting beta-lactamases, thus extending their spectrum activity. Combinations of sulbactam with beta-lactam antibiotics have been used successfully for the therapy of infections caused by organisms resistant to the antibiotic alone. Pharmacological action: enzyme inhibitors, antibiotics, lactam. Chemical name: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)- (12 Dec 1998) |
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| ampicillin | <drug> Penicillin derivative with broad spectrum activity, ampicillin resistance is often used as a marker for plasmid transfer in genetic engineering (for example pBR322 is ampicillin resistant). (13 Nov 1997) |
| ampicillin resistance | Nonsusceptibility of a microbe to the action of ampicillin, a penicillin derivative that interferes with cell wall synthesis. (12 Dec 1998) |
| abstracting and indexing | Shortening or summarizing of documents; assigning of descriptors for referencing documents. (12 Dec 1998) |
| academies and institutes | Organizations representing specialised fields which are accepted as authoritative; may be non-governmental, university or an independent research organization, e.g., national academy of sciences, brookings institution, etc. (12 Dec 1998) |
| accounts payable and receivable | Short-term debt obligations and assets occurring in the regular course of operational transactions. (12 Dec 1998) |
| aged, 80 and over | A person 80 years of age and older. (12 Dec 1998) |
| algae and fungi | Algae represent a group of spore-propagating plants, unicellular or undifferentiated into root, stem, and leaf. They include seaweed and many unicellular fresh water plants, most of which contain chlorophyll. They account for about 90% of the earth's photosynthetic activity. Fungi are eukaryotic, heterotrophic organisms that live as saprobes or parasites and include mushrooms, yeasts, smuts, molds, etc. They lack chlorophyll. (12 Dec 1998) |
| alkyl and aryl transferases | <enzyme> A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). Registry number: EC 2.5 (12 Dec 1998) |
| allergy and immunology | A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder. (12 Dec 1998) |
| alligators and crocodiles | Large, long-tailed reptiles, including caimans, of the order loricata. (12 Dec 1998) |
| Amine Precursor Uptake and Decarboxylation | <pharmacology, physiology> Paracrine cells of which argentaffin cells are an example. Usage of the term APUD is neither helpful nor memorable. Acronym: APUD (11 Nov 1997) |
| amino acids, peptides, and proteins | Amino acids and chains of amino acids connected by peptide linkages. (12 Dec 1998) |
| Anderson and Goldberger test | A test for typhus in which the patient's blood is injected into a guinea pig's peritoneal cavity. In typhus a typical temperature curve will be observed. (05 Mar 2000) |
| anniversaries and special events | Occasions to commemorate an event or occasions designated for a specific purpose. (12 Dec 1998) |