| dicarboxylic acid-CoA oxidase | <enzyme> Oxidises dicarboxylic acid CoA esters using molecular oxygen and producing hydrogen peroxide, ultimately producing a dicarboxylic acid with 2 fewer carbon atoms Registry number: EC 1.3.3.- Synonym: dicarboxylyl-CoA oxidase, dicarboxylic acid-coenzyme a oxidase (26 Jun 1999) |
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| dicarboxylic acid-CoA synthetase | <enzyme> Converts dicarboxylic acids (c5-c16) into their mono-CoA esters in the presence of ATP Registry number: EC 6.2.1.- Synonym: dicarboxylyl-CoA ligase, dicarboxylic acid-coenzyme a synthetase (26 Jun 1999) |
| dicarboxylic acid cycle | That portion of the tricarboxylic acid cycle involving the dicarboxylic acids (succinic, fumaric, malic, and oxaloacetic acids), a cyclic scheme in which certain steps of the tricarboxylic acid cycle are used with the glyoxylate cycle; important in the utilization of glyoxylic acid in microorganisms. (05 Mar 2000) |
| amino acids | Organic compounds that generally contain an amino (-nh2) and a carboxyl (-cooh) group. Twenty alpha-amino acids are the subunits which are polymerised to form proteins. (12 Dec 1998) |
| amino acids, branched-chain | Amino acids which have a branched carbon chain. (12 Dec 1998) |
| amino acids, cyclic | A class of amino acids characterised by a closed ring structure. (12 Dec 1998) |
| amino acids, peptides, and proteins | Amino acids and chains of amino acids connected by peptide linkages. (12 Dec 1998) |
| essential amino acids | Alpha-amino acids nutritionally required by an organism and which must be supplied in its diet (i.e., cannot be synthesised by the organism) either as free amino acid or in proteins. (05 Mar 2000) |
| excitatory amino acids | Endogenous amino acids released by neurons as excitatory neurotransmitters. Glutamic acid is the most common excitatory neurotransmitter in the brain. Aspartic acid has been regarded as an excitatory transmitter for many years, but the extent of its role as a transmitter is unclear. (12 Dec 1998) |
| acidic amino acid | An Amino acid with a second acid moiety, e.g., glutamic acid, aspartic acid, cysteic acid. (05 Mar 2000) |
| activated amino acid | The product formed by the condensation of the acyl radical of an amino acid and adenosine 5'-monophosphate (originally in the form of adenosine 5'-triphosphate, with elimination of a pyrophosphoric group). Formed in the first step of protein biosynthesis. Synonym: activated amino acid. (05 Mar 2000) |
| alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid | <chemical> Alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid. An ibotenic acid homolog and glutamate agonist. The compound is the defining agonist for the ampa subtype of glutamate receptors (receptors, ampa). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. Pharmacological action: excitatory amino acid agonists. Chemical name: 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo- (12 Dec 1998) |
| alpha-amino acid | Typically, an amino acid of the general formula R-CHNH2-COOH (i.e., the NH2 in the a position); the l forms of these are the hydrolysis products of proteins. In rarer usages, this class of molecules also includes alpha-amino phosphoric acids and alpha-aminosulfonic acids. (05 Mar 2000) |
| alpha-amino acid esterase | <enzyme> Converts alpha-amino acid esters and water to alpha-amino acids and alcohol Registry number: EC 3.1.1.43 Synonym: alpha-amino acid ester hydrolase (26 Jun 1999) |
| alpha-amino-beta-ketoadipic acid | 2-Amino-3-oxo-1,6-hexanedioic acid;an intermediate of porphobilinogen synthesis formed by d-aminolevulinic acid synthase from succinyl-CoA and glycine; it rapidly decarboxylates to d-aminolevulinic acid. (05 Mar 2000) |