| Addison's anaemia | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
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| Addison's clinical planes | A series of plane's used as landmarks in thoracoabdominal topography; the trunk is divided vertically by a median plane from the upper border of the manubrium of the sternum to the pubic symphysis, by a lateral plane drawn vertically on either side through a point half way between the anterior superior iliac spine and the median plane at the interspinal plane, and by an interspinal plane passing vertically through the anterior superior iliac spine on either side; transversely the trunk is divided by a transthoracic plane passing across the thorax 3.2 cm above the lower border of the body of the sternum, by a transpyloric plane midway between the jugular notch of the sternum and the pubic symphysis, corresponding to the disc between the first and second lumbar vertebrae, and by an intertubercular plane passing through the iliac tubercles and cutting usually the fifth lumbar vertebra; the plane's formed on these lines, and also on transverse plane's cutting the upper edge of the manubrium and the upper edge of the pubic symphysis, constitute the clinical plane's of Addison. (05 Mar 2000) |
| Addison's disease | <endocrinology> A rare endocrine disease that results from the underproduction of aldosterone and cortisol (hormones) by the adrenal glands. Symptoms include weakness, low blood pressure, anaemia, low blood sugar and electrolyte abnormalities. (27 Sep 1997) |
| Addison, Christopher | <person> English anatomist, 1869-1951. See: Addison's clinical planes. (05 Mar 2000) |
| Addison, Thomas | <person> English physician, 1793-1860. See: Addison's anaemia, Addison's disease, addisonian anaemia, addisonian crisis, Addison-Biermer disease. (05 Mar 2000) |
| Addison-Biermer disease | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| addisonian | Relating to or described by Thomas Addison; usually used in relation to pernicious anaemia (05 Mar 2000) |
| addisonian anaemia | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| addisonian crisis | <endocrinology> An abrupt life-threatening state which is caused by insufficient production of cortisol by the adrenal gland. A typical finding in Addison's disease. Individuals who have been taking corticosteroids (glucocorticoids) for a prolonged period of time (weeks to months) are at risk for acute adrenal crisis if the medication is stopped abruptly. For this reason, corticosteroid medication are withdrawn slowly on a diminishing dosing schedule. Symptoms include low blood pressure (shock), weakness, headache, vomiting, fever chills, tachycardia and sweating. Treatment includes blood pressure support and intravenous hydrocortisone. See: addison's disease (15 Jan 1998) |
| addisonian syndrome | Adrenocortical insufficiency usually as the result of idiopathic atrophy or destruction of both adrenal glands by tuberculosis, an autoimmune process, or other diseases; characterised by fatigue, decreased blood pressure, weight loss, increased melanin pigmentation of the skin and mucous membranes, anorexia, and nausea or vomiting; without appropriate replacement therapy, it can progress to acute adrenocortical insufficiency. Synonym: Addison's disease, addisonian syndrome, hyposupradrenalism, morbus Addisonii. (05 Mar 2000) |
| disease, addison's | Long-term underfunction of the outer portion of the adrenal gland. In medical terms, chronic insufficiency of the adrenal cortex. This may be due to a number of different insults to the adrenal including physical trauma, haemorrhage, and tuberculosis of the adrenal, and destruction of the cells in the pituitary gland that secrete ACTH (adrenocorticotropic hormone) which normally drives the adrenal. Addison's disease is characterised by bronzing of the skin, anaemia, weakness, and low blood pressure. The U.S. President J.F. Kennedy is said to have had Addison's disease. Named after the British physician Thomas Addison (1793-1860). (12 Dec 1998) |
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