| absolute CD4 count | The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count. (12 Dec 1998) |
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| absolute eosinophil count | <haematology, investigation> A measurement (cells per microlitre) of the number of eosinophils in a blood specimen. This measurement is useful in the evaluation of autoimmune disease, allergies, eczema, leukaemia, asthma and hay fever. Normal absolute eosinophil counts are less than 350 cells/mcl (microlitre). (27 Sep 1997) |
| CD4 count, absolute | The number of helper T-lymphocytes in a cubic millimeter of blood. With HIV, the absolute CD4 count declines as the infection progresses. The absolute CD4 count is frequently used to monitor the extent of immune suppression in persons with HIV. Also called a T4 count. (12 Dec 1998) |
| anionic neutrophil activating peptide | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| band neutrophil | <pathology> Immature neutrophils released from the bone marrow reserve in response to acute demand. (18 Nov 1997) |
| mature neutrophil | A fully matured neutrophil that has at least 2 (and as many as 5) distinct lobes in the nucleus and manifests active ameboid motion. Synonym: mature neutrophil. (05 Mar 2000) |
| monocyte derived neutrophil chemotactic factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| segmented neutrophil | A fully matured neutrophil that has at least 2 (and as many as 5) distinct lobes in the nucleus and manifests active ameboid motion. Synonym: mature neutrophil. (05 Mar 2000) |
| hypersegmented neutrophil | An aged and degenerated neutrophil in which there may be 6 to 10 lobes in the nucleus. Immature neutrophil, a young neutrophil; the term is usually used with reference to stab neutrophil's (or other "juvenile" neutrophil's), neutrophilic granulocytes in which the nucleus is indented but not distinctly segmented. Juvenile neutrophil, any cell of the granulocytic series in which the neutrophilic granules are recognizable and the nucleus is indented (the first phase of segmentation). (05 Mar 2000) |
| stab neutrophil | <pathology> Immature neutrophils released from the bone marrow reserve in response to acute demand. (18 Nov 1997) |
| neutrophil | <haematology> A granulocyte, a white blood cell. (18 Nov 1997) |
| neutrophil activating factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| neutrophil activating protein | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |
| neutrophil activation | The process in which the neutrophil is stimulated by diverse substances, resulting in degranulation and/or generation of reactive oxygen products, and culminating in the destruction of invading pathogens. The stimulatory substances, including opsonised particles, immune complexes, and chemotactic factors, bind to specific cell-surface receptors on the neutrophil. (12 Dec 1998) |
| neutrophil chemotactant factor | <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes. It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4. Acronym: IL-8 (12 Dec 1998) |