| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
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| abelson leukaemia virus | A defective murine leukaemia virus capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukaemia after superinfection with friend, moloney, or rauscher virus. (12 Dec 1998) |
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| Moloney murine leukaemia virus | <molecular biology, virology> Replication competent retrovirus (Oncovirinae) that causes leukaemia in mice, isolated by Moloney from cell free extracts made from a transplantable mouse sarcoma. (18 Nov 1997) |
| murine leukaemia virus | <virology> A group of type C retroviruses infecting mice and causing in some strains lymphatic leukaemia after a long latent period. Nearly all are replication competemt and v onc minus. See: Abelson leukaemia virus. (18 Nov 1997) |
| Friend murine leukaemia virus | <virology> Murine leukaemia virus isolated by Charlotte Friend in 1956 whilst attempting to transmit the Erlich ascites tumour by cell free extracts. Causes an unusual erythroblastosis like leukaemia, in which anaemia is accompanied by large numbers of nucleated red cells in blood. does not carry a host derived oncogene, but seems to induce tumours by proviral insertion into specific regions of host genome. (18 Nov 1997) |
| murine leukaemia | A leukaemic disorder of mice caused by a number of different type C retroviruses. (05 Mar 2000) |
| leukaemia viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) producing leukaemia in mice. It is commonly induced by injecting filtrates of propagable tumours into newborn mice. The gross strain (gross virus) occurs spontaneously in inbred mice, but none of the other strains occurs naturally. (12 Dec 1998) |
| Abelson, Herbert T | <person>U.S. Paediatrician, *1941. See: Abelson murine leukaemia virus. (05 Mar 2000) |
| gastroenteritis virus, murine | A species of the coronavirus genus causing hepatitis in mice. Four strains have been identified as mhv 1, mhv 2, mhv 3, and mhv 4 (also known as jhm, which is neurotropic and causes disseminated encephalomyelitis with demyelination as well as focal liver necrosis). (12 Dec 1998) |
| Moloney murine sarcoma virus | <molecular biology, virology> Replication defective retrovirus, source of the oncogene v mos, responsible for inducing fibrosarcomas in vivo and transforming cells in culture. (18 Nov 1997) |
| murine sarcoma virus | A seemingly defective retrovirus that produces sarcomas in mice when growing in the presence of a "helper" virus; e.g., mouse leukaemia virus. (05 Mar 2000) |
| theiler's murine encephalomyelitis virus | A species of cardiovirus which causes poliomyelitis in rats. It should not be confused with the strain of encepalomyocarditis virus called encephalomyelitis virus, murine, which is also a cardiovirus. (12 Dec 1998) |
| encephalomyelitis virus, murine | A strain of encephalomyocarditis virus, a species of cardiovirus, usually causing an inapparent intestinal infection in mice. A small number of mice may show signs of flaccid paralysis. (12 Dec 1998) |
| avian leukaemia virus | <virology> Group of C type RNA tumour viruses (Oncovirinae) that cause various leukaemias and other tumours in birds. The acute leukaemia viruses, that are replication defective and require helper viruses, include avian erythroblastosis (AEV), myeloblastosis (AMV) and myelo cytomatosis viruses. AEV carries two transforming genes, v erbA and v erbB, the cellular homologue of the latter is the structural gene for the epidermal growth factor receptor. AMV carries v myb and causes a myeloid leukaemia, avian myelocytomatosis virus carries v myc. The avian lymphatic leukaemia viruses (ALV) are also Retroviridae but are replication competent and induce neoplasia only after several months, they often occur in conjunction with replication defective leukaemia viruses. (02 Jan 1998) |
| bovine leukaemia virus | A type C retrovirus in the subfamily Retrovirinae, commonly infecting cattle, especially dairy cows; in a small proportion of infected cattle, it will cause enzootic bovine leukosis. Synonym: bovine leukosis virus. (05 Mar 2000) |
| radiation leukaemia virus | A murine leukaemia virus isolated from radiation-induced lymphomas in c57bl mice. It is leukemogenic, thymotrophic, can be transmitted vertically, and replicates only in vivo. (12 Dec 1998) |