| azacitidine | <chemical> An antimetabolite antineoplastic agent with general properties similar to those of cytarabine. It inhibits cellular pyrimidine synthesis and has been used mainly in the treatment of acute non-lymphoblastic leukaemia. Pharmacological action: antimetabolites, antineoplastic. Chemical name: 1,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl- (12 Dec 1998) |
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| azacosterol | <chemical> 17-[[3-(dimethylamino)propyl]methylamino]-androst-5-en-3-ol. Diaza derivative of cholesterol which acts as a hypocholesteraemic agent by blocking delta-24-reductase, which causes the accumulation of desmosterol. Induces myotonia. It is also used as an avian chemosterilant. Synonym: sc-12937. Chemical name: Androst-5-en-3-ol, 17-((3-(dimethylamino)propyl)methylamino)-, (3beta,17beta)- (12 Dec 1998) |
| azacrine | 2-Methoxy-6-chloro-9-(5'-diethylamino-2'-pentyl)amino-3-azoacridine;an antimalarial; an effective schizontocide in acute falciparum infection. (05 Mar 2000) |
| azacyclonol hydrochloride | Gamma-Pipradol hydrochloride; a,alpha-diphenyl-4-piperidine-methanol hydrochloride;a structural isomer of pipradol hydrochloride partially antagonistic to its actions, used with varying results in the treatment of hallucinations and confusion. (05 Mar 2000) |
| azaguanine | <chemical> 5-amino-1,4-dihydro-7h-1,2,3-triazolo(4,5-d)pyrimidin-7-one. One of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. Pharmacological action: antimetabolites, antineoplastic. Chemical name: 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-1,4-dihydro- (12 Dec 1998) |
| azaheterocycle N-methyltransferase | <enzyme> Catalyses the n-methylation of nicotine to n-methylnicotinium Registry number: EC 2.1.1.- Synonym: azh-n-methyltransferase, nicotine n-methyltransferase (26 Jun 1999) |
| azalea | <botany> A genus of showy flowering shrubs, mostly natives of China or of North America; false honeysuckle. The genus is scarcely distinct from Rhododendron. Origin: NL, fr. Gr. Dry, so called because supposed to grow best in dry ground. Source: Websters Dictionary (01 Mar 1998) |
| azamethonium bromide | A ganglionic blocking agent. Chemical name: [(Methylimino)diethylene]bis-[ethyldimethylammonium bromide]. (05 Mar 2000) |
| azaperone | <chemical> A butyrophenone used in the treatment of psychoses. Pharmacological action: antipsychotic agents, butyrophenone, dopamine antagonists, sedatives, nonbarbiturate. Chemical name: 1-Butanone, 1-(4-fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)- (12 Dec 1998) |
| azapetine phosphate | A potent adrenergic (alpha-receptor) blocking agent similar in action and uses to those of tolazoline; used in the treatment of peripheral vascular diseases. Chemical name: 6-Allyl-6,7-dihydro-5H-dibenz[c.e]azepine phosphate. (05 Mar 2000) |
| azaribine | An antipsoriatic agent no longer used because of a high incidence of severe adverse reactions. Chemical name: 2',3',5'-Triacetyl derivative of 6-azauridine. (05 Mar 2000) |
| azarole | <botany> The Neapolitan medlar (Crataegus azarolus), a shrub of southern Europe; also, its fruit. Origin: F. Azerole, the name of the fruit, fr. Ar. Az-zo'rr: cf. It. Azzeruolo, Sp. Acerolo. Source: Websters Dictionary (01 Mar 1998) |
| azaserine | <drug> An analogue of glutamine that competitively inhibits various pathways in which glutamine is metabolised, hence an antibiotic and antitumour agent. (18 Nov 1997) |
| azaspirodecanedione | A class of antianxiety agents not chemically or pharmacologically related to other classes of sedative and anxiolytic drugs; e.g., buspirone hydrochloride. (05 Mar 2000) |
| azasteroids | Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with nitrogen atoms. (12 Dec 1998) |