| atropine sulfate | An anticholinergic; a widely used soluble salt of atropine. (05 Mar 2000) |
|---|
| atropine | <drug> A toxic alkaloid extracted from belladonna and other members of thenightshade family, it is typically used to dilate the eye and to stopmuscular spasms. Pharmacologic action: Parasympatholytic. Competitive blockade of acetylcholine at muscarinic receptors. Increases sinus node automaticity and AV conduction. Uses: Treat bradycardia, asystole, and AV block Dose: 0.5 - 1.0 mg for bradycardia every 3 - 5 min to a total dose of 0.04 mg/kg. Doses smaller than 0.5 mg can cause a paradoxical bradycardia due to sympathomimetic effects Typically 3 mg is adequate to completely block vagal effects Atropine is well absorbed via endotracheal route - administer 1-2 mg diluted in 10 mL sterile water or normal saline. Potential complications: 1. Tachyarrhythmias 2. Exacerbation of myocardial ischemia 3. Low dose may cause paradoxical bradycardia 4. Dry mouth, urinary retention, flushed and hot skin 5. Crosses blood-brain barrier which can cause delirium Note: The denervated heart will not respond to atropine. (15 Mar 2000) |
|---|---|
| atropine dehydrase | <enzyme> Proposed mechanism for conversion of atropine or scopolamine to apoatropine or aposcopolamine via a mechanism using hydroxysteroid sulfotransferase by guinea pig liver Registry number: EC 2.8.2.- Synonym: scopolamine dehydrase (26 Jun 1999) |
| atropine derivatives | Analogs and derivatives of atropine. (12 Dec 1998) |
| atropine methonitrate | The methylnitrate of atropine, with the same actions and uses as atropine, but less lipid-soluble and hence with fewer central nervous system effects; a quaternary compound. (05 Mar 2000) |
| atropine methylbromide | A quaternary derivative of atropine that is less lipid soluble and hence produces fewer central nervous system actions; a cycloplegic. Synonym: atropine methylbromide. (05 Mar 2000) |
| atropine test | If an injection of atropine relieves bradycardia, the condition is due to action of the vagus; if it does not, the condition may be due to an affection of the heart itself. Synonym: atropine test. (05 Mar 2000) |
| acid sulfate | A salt containing HSO4-. Synonym: acid sulfate. (05 Mar 2000) |
| active sulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |
| adenine sulfate | Adenine conjugated with sulfuric acid; used to stimulate leukocyte production in agranulocytosis. (05 Mar 2000) |
| adenylyl sulfate-ammonia adenylyltransferase | <enzyme> Forms adenosine 5'-phosphoramidate Registry number: EC 2.7.7.- Synonym: adenylyl sulphate-ammonia adenylyltransferase, as-aat (26 Jun 1999) |
| aluminum ammonium sulfate | AlNH4(SO4)2;an astringent. (05 Mar 2000) |
| aluminum potassium sulfate | AlK(SO4)2;an astringent and styptic; also used in veterinary medicine for ulcerative stomatitis, leukorrhoea, and conjunctivitis. Synonym: potassium alum. (05 Mar 2000) |
| aluminum sulfate octadecahydrate | Astringent detergent for skin ulcers. Synonym: cake alum. (05 Mar 2000) |
| amikacin sulfate | An aminoglycoside antibiotic agent with antimicrobial activity similar to that of kanamycin; also effective against Pseudomonas aeruginosa. (05 Mar 2000) |
| ammonium ferric sulfate | An astringent and styptic. Synonym: ammonium ferric sulfate, ferric alum, iron alum. (05 Mar 2000) |