| atropine | <drug> A toxic alkaloid extracted from belladonna and other members of thenightshade family, it is typically used to dilate the eye and to stopmuscular spasms. Pharmacologic action: Parasympatholytic. Competitive blockade of acetylcholine at muscarinic receptors. Increases sinus node automaticity and AV conduction. Uses: Treat bradycardia, asystole, and AV block Dose: 0.5 - 1.0 mg for bradycardia every 3 - 5 min to a total dose of 0.04 mg/kg. Doses smaller than 0.5 mg can cause a paradoxical bradycardia due to sympathomimetic effects Typically 3 mg is adequate to completely block vagal effects Atropine is well absorbed via endotracheal route - administer 1-2 mg diluted in 10 mL sterile water or normal saline. Potential complications: 1. Tachyarrhythmias 2. Exacerbation of myocardial ischemia 3. Low dose may cause paradoxical bradycardia 4. Dry mouth, urinary retention, flushed and hot skin 5. Crosses blood-brain barrier which can cause delirium Note: The denervated heart will not respond to atropine. (15 Mar 2000) |
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| atropine dehydrase | <enzyme> Proposed mechanism for conversion of atropine or scopolamine to apoatropine or aposcopolamine via a mechanism using hydroxysteroid sulfotransferase by guinea pig liver Registry number: EC 2.8.2.- Synonym: scopolamine dehydrase (26 Jun 1999) |
| atropine derivatives | Analogs and derivatives of atropine. (12 Dec 1998) |
| atropine methonitrate | The methylnitrate of atropine, with the same actions and uses as atropine, but less lipid-soluble and hence with fewer central nervous system effects; a quaternary compound. (05 Mar 2000) |
| atropine methylbromide | A quaternary derivative of atropine that is less lipid soluble and hence produces fewer central nervous system actions; a cycloplegic. Synonym: atropine methylbromide. (05 Mar 2000) |
| atropine sulfate | An anticholinergic; a widely used soluble salt of atropine. (05 Mar 2000) |
| atropine test | If an injection of atropine relieves bradycardia, the condition is due to action of the vagus; if it does not, the condition may be due to an affection of the heart itself. Synonym: atropine test. (05 Mar 2000) |
| accessory organs of the eye | The eyelids, with lashes and eyebrows, lacrimal apparatus, conjunctival sac, and extrinsic muscles of the eyeball. Synonym: organa oculi accessoria, accessory organs, accessory visual apparatus, adnexa oculi, appendages of eye. (05 Mar 2000) |
| accommodation of eye | The increase in thickness and convexity of the eye's lens in order to focus the image of an external object upon the retina. (05 Mar 2000) |
| amaurotic cat's eye | A yellow reflex from the pupil in cases of retinoblastoma or pseudoglioma. (05 Mar 2000) |
| anterior chamber of eye | The space between the cornea anteriorly and the iris/pupil posteriorly, filled with a watery fluid (aqueous humor) and communicating through the pupil with the posterior chamber. Synonym: camera anterior bulbi, camera oculi anterior, camera oculi major. (05 Mar 2000) |
| anterior eye segment | That part of the eyeball anterior to the lens. (12 Dec 1998) |
| antibiotic eye drops | <pharmacology> A medication that is pH balanced to allow placement into the eye for the purpose of killing bacteria. Examples include: Bleph-10, Chloromycetin, Cortisporin-Ophthalmic, Gantrisin, Genoptic, Gentacidin, Garamycin, Gantrisin, Ilotycin, Sodium Sulamyd and Sulphair. (27 Sep 1997) |
| aphakic eye | The eye from which the lens is absent. (05 Mar 2000) |
| appendages of eye | The eyelids, with lashes and eyebrows, lacrimal apparatus, conjunctival sac, and extrinsic muscles of the eyeball. Synonym: organa oculi accessoria, accessory organs, accessory visual apparatus, adnexa oculi, appendages of eye. (05 Mar 2000) |