| ATP citrate lyase |
an enzyme of the lyase class that catalyzes the ATP-dependent cleavage of citrate to form oxaloacetate and acetate, the latter then condensing with coenzyme A to form acetyl coenzyme A. The reaction is part of the mechanism by which acetyl coenzyme A produced in the mitochondria from pyruvate can be transported to the cytosol to be used in fatty acid synthesis. In EC nomenclature, called ATP citrate (pro-S) lyase [EC 4.1.3.8]. Called also citrate cleavage enzyme.
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