| amsacrine | <chemical> N-(4-(9-acridinylamino)-3-methoxyphenyl)methanesulfonamide. Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukaemias and malignant lymphomas, but has poor activity in the treatment of solid tumours. It is frequently used in combination with other antineoplastic agent in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. Pharmacological action: antineoplastic agent. Chemical name: Methanesulfonamide, N-(4-(9-acridinylamino)-3-methoxyphenyl)- (12 Dec 1998) |
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| Amsler test | Projection of a visual field defect onto an Amsler chart. (05 Mar 2000) |
| Amsler's chart | A 10-cm square divided into 5-mm squares upon which an individual may project a defect in the central visual field. (05 Mar 2000) |
| Amsler, Marc | <person> Swiss ophthalmologist, 1891-1968. See: Amsler's chart, Amsler test. (05 Mar 2000) |
| Amsterdam syndrome | <syndrome> A congenital anomaly characterised by impaired development, mental retardation, characteristic facies with snyophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym: Amsterdam syndrome, Cornelia de Lange syndrome. (05 Mar 2000) |