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ACP <abbreviation> Acyl carrier protein.
(05 Mar 2000)
ACP-acetyltransferase Enzyme transferring acetyl from acetyl-CoA to acyl carrier protein and releasing CoA to begin fatty acid synthesis.
Synonym: acetyl transacylase.
(05 Mar 2000)
ACP-malonyltransferase <enzyme> An enzyme transferring malonyl from malonyl-CoA to acyl carrier protein and releasing free CoA; a key step in fatty acid synthesis.
Synonym: malonyl transacylase.
(05 Mar 2000)
acyl-ACP dehydrogenase enoyl-ACP reductase (NADPH)
acyl-malonyl-ACP synthase <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex.
Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase.
(05 Mar 2000)
beta-ketoacyl-ACP reductase A part of the fatty acid synthase complex; an enzyme reversibly reacting 3-oxoacyl-ACP with NADPH to form d-3-hydroxyacyl-ACP and NADP+.
Synonym: beta-ketoacyl-ACP reductase.
(05 Mar 2000)
beta-ketoacyl-ACP synthase <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex.
Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase.
(05 Mar 2000)
crotonyl-ACP reductase 1. An enzyme catalyzing hydrogenation of acyl-ACP complexes to 2,3-dehydroacyl-ACP's, with NAD+ as hydrogen acceptor; important in fatty acid metabolism.
Synonym: crotonyl-ACP reductase.
2. A variant enzyme has been found carrying out the same reaction as enoyl-ACP reductase, but with NADP+ as hydrogen acceptor.
Synonym: acyl-ACP dehydrogenase, acyl-ACP reductase.
(05 Mar 2000)
holo-ACP synthase <enzyme> An enzyme catalyzing transfer of the 4'-phosphopantetheinyl residue from CoA to a serine of apo-ACP (acyl carrier protein) to form holo-ACP, releasing adenosine 3',5'-bisphosphate; a required step if fatty acid biosynthesis is to function.
(05 Mar 2000)
enoyl-ACP reductase 1. An enzyme catalyzing hydrogenation of acyl-ACP complexes to 2,3-dehydroacyl-ACP's, with NAD+ as hydrogen acceptor; important in fatty acid metabolism.
Synonym: crotonyl-ACP reductase.
2. A variant enzyme has been found carrying out the same reaction as enoyl-ACP reductase, but with NADP+ as hydrogen acceptor.
Synonym: acyl-ACP dehydrogenase, acyl-ACP reductase.
(05 Mar 2000)
3-oxoacyl-ACP reductase A part of the fatty acid synthase complex; an enzyme reversibly reacting 3-oxoacyl-ACP with NADPH to form d-3-hydroxyacyl-ACP and NADP+.
Synonym: beta-ketoacyl-ACP reductase.
(05 Mar 2000)
3-oxoacyl-ACP synthase <enzyme> An enzyme condensing malonyl-ACP and acyl-cys-protein to 3-oxoacyl-ACP + cys-protein + CO2, and similar reactions, as steps in fatty acid synthesis; cys-protein is also a part of the fatty acid synthase complex.
Synonym: acyl-malonyl-ACP synthase, beta-ketoacyl-ACP synthase.
(05 Mar 2000)
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