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a1-acid glycoprotein <biology> Plasma protein of mammals and birds, 38% carbohydrate. In humans a single chain glycoprotein of 39 kD. Increased levels are associated with inflammation, pregnancy and various diseases.
(18 Nov 1997)
a1-antitrypsin A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin.
Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor.
(05 Mar 2000)
a1-lipoprotein A lipoprotein fraction of relatively low molecular weight, high density, rich in phospholipids, and found in the a1-globulin fraction of human plasma.
(05 Mar 2000)
a1-trypsin inhibitor A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin.
Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor.
(05 Mar 2000)
a1PI Symbol for human alpha 1-proteinase inhibitor.
(05 Mar 2000)
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