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4-aminopyridine <chemical> A potassium channel blocker. It is used primarily as a research tool and is helpful in characterizing subtypes of potassium channels. It has been used clinically in lambert-eaton syndrome and multiple sclerosis because by blocking potassium channels it prolongs action potentials thereby increasing transmitter release at the neuromuscular junction (and elsewhere).
Chemical name: 4-Pyridinamine
(12 Dec 1998)
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