25-hydroxyvitamin D3 : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 1 페이지: 1

25-Hydroxyvitamin D3 1-alpha-Hydroxylase - 새창 A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).
Synonyms : 25-Hydroxycholecalciferol-1-Hydroxylase, 25-Hydroxyergocalciferol 1-alpha-Hydroxylase, 25-Hydroxyvitamin D 1-alpha-Hydroxylase, 25-Hydroxyvitamin D(3) 1 alpha-Hydroxylase, 25-Hydroxyvitamin D2 1-hydroxylase, 1-alpha-Hydroxylase, 25-Hydroxyergocalciferol