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17a-hydroxyprogesterone 17a-Hydroxy-4-pregnen-3,20-dione;medical use is similar to that of progesterone. The acetate is an orally effective derivative, useful in conditions in which parenterally administered progesterone or the caproate is indicated; it possesses some androgenic potency and may cause virilizing changes in a female foetus. The caproate or hexanoate has essentially the same actions and uses as progesterone, but is more potent and has a longer duration of action. A precursor of the androgens and adrenocortical hormones.
(05 Mar 2000)
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