| 영문 | angiotensin | 한글 | 안지오텐신 |
|---|---|---|---|
| 설명 | 콩팥에서 신장의 혈류와 혈압을 감지하는 세포인 치밀반점(macula densa)과 토리곁세포(JG cell)에서 혈류와 혈압의 저하가 있을 경우에 레닌이라는 물질이 분비되게 된다. 이 레닌이라는 물질은 혈중에 존재하는 안지오텐신이라는 물질을 안지오텐신 I으로 변화시키고 이 안지오텐신 I이라는 물질은 안지오텐신 I 전환효소에 의해서 안지오텐신II라는 물질로 된다. 안지오텐신과 안지오텐신 I이라는 물질은 그 작용이 거의 없지만 안지오텐신 II라는 물질은 강력하게 혈관수축을 시키고 이로 인해서 혈압의 상승을 가져오며 동시에 부신을 자극하여 알도스테론을 분비하게 한다. 안지오텐신이란 혈관을 수축시키고 알도스테론의 분비를 유도함으로써 혈압의 상승을 가져오는 물질이다. 그리고 그 작용은 레닌-안지오텐신-알도스테론으로 이어지는 체계에 의해서 조절되고 이루어진다. |
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| 영문 | hepatic portal system | 한글 | 간문맥계 |
|---|---|---|---|
| 설명 | 위, 작은창자이나 큰창자에서 영양분을 흡수하기 위한 모세혈관조직은 모두 간으로 연결된다. 즉 소화기에 흡수한 영양분이 가득한 피는 모두 간으로 연결되는데 이것을 문맥계라고 한다. |
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| 영문 | system | 한글 | 계, 계통 |
|---|---|---|---|
| 설명 | 인체를 구성하는 계는 다음과 같이 구분된다. 1) 심장혈관계통(cardiovascular system) 2) 호흡기계(respiratory system) 3) 소화기계(digeshive system) 4) 비뇨기계(urinary system) 5) 생식기계(genital system) 6) 혈액계(hematologic system) 7) 내분비계(endocrine system) 8) 신경계(nervous system) 9) 골격계(skeletal system) 10) 근육계(muscular system) 11) 피부계(integumentary system). |
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| 영문 | sympathetic nervous system | 한글 | 교감신경계 |
|---|---|---|---|
| 설명 | 자율신경계의 일종으로 내장기능을 주로 항진시켜 활동을 증가시키는 기능을 가진다. 자율신경계의 다른 계열인 부교감신경계는 반대로 내장기능을 억제시켜 에너지를 비축하는 기능을 가진다. 자율신경계의 해부학적 특성은 신경이 중추신경계에서 나와 목표장기에 도달하기 전에 한번의 시냅스(synapse)를 이룬다는 점이며, 따라서 자율신경계는 두 개의 신경(시냅스를 이루기 전의 절전신경과 이룬 후의 절후신경)으로 구성된다. 자율신경계중 교감신경계는 중추신경계 즉 척수 부근의 교감신경절(sympathetic ganglion)에서 시냅스가 일어나고, 부교감 신경계는 중추신경계에서 멀리 떨어진 목표 장기부근의 신경절(ganglion)에서 시냅스가 일어나는 점이 다르다. |
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| 영문 | musculoskeletal System | 한글 | 근골격계 |
|---|---|---|---|
| 설명 | 근육과 이들 근육이 붙어서 같이 활동을 수행하는 골격(뼈를 통털어 말함)을 함께 부르는 말. 따라서 여기의 근육은 모두 가로무늬근에 속하며, 수의적으로 움직일 수 있다. |
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| RAS | rapid atrial stimulation; recurrent aphthous stomatitis; reflex activating stimulus; reliability, av... |
|---|---|
| RAA | renin-angiotensin-aldosterone [system] |
| RAAS | renin-angiotensin-aldosterone system |
| RAA | Renin-Angiotensin-Aldosterone |
| RA | radioactive; ragocyte; ragweed antigen; rapidly adapting [receptors]; reactive arthritis; reciprocal... |
| RAS | Renin Angiotensin System |
|---|---|
| RAAS | Renin-Angiotensin-Aldosterone System |
| RAA | Renin-Angiotensin-Aldosterone |
| RA | Renin-angiotensin |
| T system | tubular system |
| renin-angiotensin-aldosterone system | The hormones, renin, angiotensin, and aldosterone work together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin. This is converted to angiotensin in the circulation. Angiotensin then raises blood pressure directly by arteriolar constriction and stimulates adrenal gland to produce aldosterone which promotes sodium and water retention by kidney, such that blood volume and blood pressure increase. (05 Mar 2000) |
|---|---|
| renin-angiotensin system | <physiology> A system consisting of renin, angiotensin-converting enzyme, and angiotensin II. Renin, an enzyme produced in the kidney, acts on angiotensinogen, an alpha-2 globulin produced by the liver, forming angiotensin I. The converting enzyme contained in the lung acts on angiotensin I in the plasma converting it to angiotensin II, the most powerful directly pressor substance known. It causes contraction of the arteriolar smooth muscle and has other indirect actions mediated through the adrenal cortex. (25 Jun 1999) |
| renin | <enzyme> An enzyme of the hydrolase class that catalyses cleavage of the leucine leucine bond in angiotensin to generate angiotensin. 1. The enzyme is synthesised as inactive prorenin in the kidney and released into the blood in the active form in response to various metabolic stimuli. Not to be confused with rennin (chymosin). (25 Jun 1999) |
| plasma renin activity | The estimation of renin in plasma by measuring the rate of formation of angiotensin I or II. (05 Mar 2000) |
| angiotensin | <hormone> A family of oligopeptides ranging in size from angiotensin precursors with 14 amino acids to the active vasoconstrictor angiotensin II with 8 amino acids, or their analogs or derivatives. The amino acid content varies with the species and changes in that content produce antagonistic or inactive compounds. Angiotensinogen (renin substrate) is a 60 kD polypeptide released from the liver and cleaved in the circulation by renin to form the biologically inactive decapeptide angiotensin I. This is in turn cleaved to form active angiotensin II by Angiotensin-converting Enzyme (ACE). Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. (12 Aug 2000) |
| angiotensin amide | <chemical> 1-l-asparagine-5-l-valine-angiotensin II. The octapeptide amide of bovine angiotensin II used to increase blood pressure by vasoconstriction. Pharmacological action: vasoconstrictor agents. Chemical name: Angiotensin II, 1-L-asparagine-5-L-valine- (12 Dec 1998) |
| angiotensin-converting enzyme | <enzyme> This hydrolase enzyme cleaves the decapeptide angiotensin I (biologically inactive) to form active angiotensin II by angiotensin-converting enzyme which removes a dipeptide (histidylleucine) from angiotensin I. Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. Elevations in angiotensin converting enzyme are seen sarcoidosis, histoplasmosis, alcoholic cirrhosis, asbestosis, berylliosis, diabetes, Hodgkin's disease, hyperthyroidism, amyloidosis, primary biliary cirrhosis, idiopathic pulmonary fibrosis, pulmonary embolism, scleroderma, silicosis, tuberculosis, Gaucher's disease and leprosy. The normal values are 18 to 67 U/ml over 20 years of age (people under 20 have higher levels). Drugs that inhibit ACE are used to treat hypertension and congestive heart failure. See: angiotensin-converting enzyme inhibitor Acronym: ACE (12 Aug 2000) |
| angiotensin-converting enzyme inhibitor | <pharmacology> A class of drugs used in the treatment of hypertension and heart failure. They exert their haemodynamic effect mainly by inhibiting the renin-angiotensin system and produce a reduction of peripheral arterial resistance. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. (14 Aug 2000) |
| angiotensin-converting enzyme secretase | <enzyme> Converts ace from a membrane-bound to a soluble form; not inhibited by thiol, serine or acid enzyme inhibitor but is inhibited by edta and 1,10-phenanthroline Registry number: EC 3.4.99.- Synonym: ace secretase (26 Jun 1999) |
| angiotensin I | <chemical> The decapeptide precursor of angiotensin II, generated by the action of renin on angiotensinogen. It has limited pharmacologic activity. Chemical name: Angiotensin I (12 Dec 1998) |
| angiotensin II | <chemical> The active form of angiotensin. An octapeptide found in blood, it is synthesised from angiotensin I and quickly destroyed. Angiotensin II causes profound vasoconstriction with resulting increase in blood pressure. The clinically and experimentally used bovine form has valine in position 5 where the human form has isoleucine. Pharmacological action: vasoconstrictor agents. Chemical name: Angiotensin II (12 Dec 1998) |
| angiotensin III | <chemical> A heptapeptide formed by the enzymatic hydrolysis of angiotensin II. It has greater activity than angiotensin II for stimulating aldosterone synthesis and in the release of prostaglandins but only 20% of the pressor activity. Chemical name: Angiotensin II, 1-de-L-aspartic acid- (12 Dec 1998) |
| angiotensin I (Phe 8-His 9) hydrolase | <enzyme> Cleaves the cooh-terminal dipeptide his(9)-leu(10) from the decapeptide angiotensin i Registry number: EC 3.4.15.- Synonym: atypical angiotensin-converting enzyme (26 Jun 1999) |
| angiotensin precursor | angiotensin |
| angiotensin-related carboxypeptidase | <enzyme> Rat and bovine brain synaptosomal enzyme can hydrolyze angiotensin I to des-leu angiotensin I, but no further Registry number: EC 3.4.- Synonym: angiotensin-specific carboxypeptidase (26 Jun 1999) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|