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APV Avian polyomavirus
HaPV Hamster polyomavirus
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polyomavirus <virology> A papovavirus (genus Polyomavirus, family Papovaviridae) which is a DNA tumour virus with very small genome.
Polyoma was isolated from mice, in which it causes no obvious disease, but when injected at high titre into baby rodents, including mice, it causes tumours of a wide variety of histological types (hence polyoma).
In vitro, infected mouse cells are permissive for virus replication and thus are killed, whilst hamster cells undergo abortive infection and at a low frequency become transformed.
It is capable of producing parotid tumours in mice and sarcomas in hamsters as well as tumours in other laboratory animals.
Synonym: mouse parotid tumour virus.
(22 Sep 2002)
polyomavirus hominis 1 <virology> A species of polyomavirus apparently infecting over 90% of children but not clearly associated with any clinical illness in childhood.
The virus remains latent in the body throughout life and can be reactivated under certain circumstances.
(12 Dec 1998)
polyomavirus hominis 2 <virology> A species of polyomavirus, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy.
The patient's initials j.c. Gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
(12 Dec 1998)
polyomavirus macacae <virology> A species of polyomavirus isolated from rhesus monkey kidney tissue, which produces malignancy in human and newborn hamster kidney cell cultures and tumours on inoculation into newborn hamsters.
(12 Dec 1998)
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antigens, polyomavirus transforming Polyomavirus antigens which cause infection and cellular transformation. The large t antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle t antigen for the transformation of primary cells. Small t antigen is necessary for the completion of the productive infection cycle.
(12 Dec 1998)
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  • Polyomavirus - »õâ A genus of potentially oncogenic viruses of the family POLYOMAVIRIDAE. These viruses are normally present in their natural hosts as latent infections. The virus is oncogenic in hosts different from the species of origin.
    Synonyms : Hamster polyomavirus, Polyoma Virus, Polyoma Viruses, Bovine polyomaviruses, Hamster polyomaviruses, Murine polyomaviruses, Polyomaviruses, Virus, Polyoma, Viruses, Polyoma, polyomavirus, Bovine, polyomavirus, Hamster, polyomavirus, Murine, polyomaviruses, Bovine
  • Polyomavirus Infections - »õâ Infections with POLYOMAVIRUS, which are often cultured from the urine of kidney transplant patients. Excretion of BK VIRUS is associated with ureteral strictures and CYSTITIS, and that of JC VIRUS with progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL).
    Synonyms : Polyomavirus Infection
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polyomavirus (Poly
Ãâó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
polyomavirus Polyomavirus is the sole genus of viruses within the family Polyomaviridae. Polyomaviruses are DNA-based, small (40-50 nanometers in diameter), and icosahedral in shape, and do not have a lipoprotein envelope. They are potentially oncogenic (tumor-causing); they often persist as latent infections in a host without causing disease, but may produce tumors in a host of a different species, or a host with an ineffective immune system. ...
Ãâó: en.wikipedia.org/wiki/Polyomavirus
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