| EMIC | emergency maternal and infant care; Environmental Mutagen Information Center |
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| EMICBACK | Environmental Mutagen Information Center Backfile |
| MUT | mutagen |
| mutagen | <chemistry, oncology> An agent that can cause an increase in the rate of mutation, includes X-rays, ultraviolet irradiation (260 nm) and various chemicals. (18 Nov 1997) |
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| mutagenesis | The development of mutations. (09 Oct 1997) |
| mutagenesis, insertional | Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA can be inserted into or adjacent to a cellular proto-oncogene. Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements, or cause unregulated expression of the proto-oncogene resulting in tumour formation. (12 Dec 1998) |
| mutagenesis, site-directed | Mutagenesis where the mutation is caused by in vitro induction directed at a specific site in a DNA molecule. The most common method involves use of a chemically synthesised oligonucleotide mutant which can hybridise with the DNA target molecule. The resulting mismatch-carrying DNA duplex may then be transfected into a bacterial cell line and the mutant strands recovered. (12 Dec 1998) |
| mutagenic | <genetics, molecular biology> Inducing genetic mutation. Origin: Gr. Gennan = to produce (18 Nov 1997) |
| mutagenicity test | <investigation> Range of tests using biological systems to see whether compounds can cause mutations. (14 Nov 1997) |
| mutagenicity tests | Tests of chemical substances and physical agents for mutagenic potential. They include microbial, insect, mammalian cell, and whole animal tests. (12 Dec 1998) |
| mutagens | Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (12 Dec 1998) |
| intercalating mutagen | A mutagen that causes frame-shift mutations by inserting itself between two adjacent bases in a genetic sequence. (09 Oct 1997) |
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| frameshift mutagen | <molecular biology> A mutagen, such as an acridine derivative, that causes a frameshift mutation; codons (base triplets) are read out of phase and different amino acids are made. (05 Mar 2000) |
Synonyms : Mutageneses
Synonyms : Activation, Insertional, Activations, Insertional, Cassette Mutageneses, Cassette Mutagenesis, Insertional Activations, Insertional Mutageneses, Insertional Mutageneses, Viral, Insertional Mutagenesis, Viral, Linker Insertion Mutagenesis, Mutageneses, Cassette
Synonyms : Mutageneses, Oligonucleotide-Directed, Mutageneses, Site-Directed, Mutageneses, Site-Specific, Mutagenesis, Oligonucleotide Directed, Mutagenesis, Site Directed, Mutagenesis, Site Specific, Oligonucleotide Directed Mutagenesis, Site Directed Mutagenesis
Synonyms : Tests, Genetic Toxicity, Toxicity Tests, Genetic, Genetic Toxicity Test, Genotoxicity Test, Mutagen Screenings, Mutagenicity Test, Screening, Mutagen, Screenings, Mutagen, Test, Genotoxicity, Tests, Genotoxicity, Toxicity Test, Genetic
Synonyms :
| mutagenic |
capable of inducing mutation (used mainly of extracellular factors such as X-rays or chemical pollution)
Ãâó: wordnet.princeton.edu/perl/webwn
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| mutagen |
any agent (physical or environmental) that can induce a genetic mutation or can increase the rate of mutation
Ãâó: wordnet.princeton.edu/perl/webwn
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| mutagenesis |
an event capable of causing a mutation
Ãâó: wordnet.princeton.edu/perl/webwn
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| mutagenesis |
Mutations are permanent, sometimes transmissible (if the change is to a germ cell) changes to the genetic material (usually DNA or RNA) of a cell. Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control during the processes such as meiosis or hypermutation. ...
Ãâó: en.wikipedia.org/wiki/Mutagenesis
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| mutagenesis |
Change(s) in the genetic constitution of a cell through alterations to its DNA.
Ãâó: www.fao.org/docrep/003/X3910E/X3910E16.htm
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| mutagen | any agent (physical or environmental) that can induce a genetic mutation or can increase the rate of mutation |
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| mutagen | an event capable of causing a mutation |
| mutagen | capable of inducing mutation (used mainly of extracellular factors such as X-rays or chemical pollution) |
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