| 영문 | macrophages, phagocyte | 한글 | 포식세포, 큰포식세포 |
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| 설명 | 1. 큰 단핵 세포로서 림프절이나 혹은 다른 여러 기관에 분포하며, 침범한 병균이나, 바이러스가 들어간 병든 세포등을 잡아먹고 이를 분해하는 기능을 가지고 있다. 따라서 면역현상에 관여하는 세포 인데, 그 크기가 커서 큰포식세포로 불린다. 2. 동물체 내에서 이물체를 처리하는 세포의 총칭. 이물체란 기생체(세균-균류-바이러스)와 비생물체(먼지-매연-가시 등)와 자체의 노화 세포이다. 이물체가 포식세포보다 작을 때는 식세포는 이것을 포식하며, 클 때는 다수의 포식세포가 이를 포위한다. 이물체는 식세포내 효소에 의해 분해되는 경우가 많은데 분해가 불가능한 경우에는 포식세포가 작은 덩어리로 되어 이물체를 체내에서 격리하기도 하고 체표에서 밖으로 방출하기도 한다. 큰포식세포는 모든 다세포 동물에 존재한다. 원생동물은 개체 자체가 포식세포(먹이를 섭취할 때)이다. 해면동물 위강 내면의 편모세포(깃세포), 강장동물과 편형동물의 소화강 상피세포에도 포식세포가 있다. |
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| MAF | macrophage activation factor; macrophage agglutinating factor; maximum atrial fragmentation; minimum... |
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| MSF | macrophage slowing factor; macrophage spreading factor; Medicins sans Frontieres [Doctors without Bo... |
| PM | after death (Lat. post mortem); after noon [Lat. post meridiem]; mean pressure; pacemaker; pantomogr... |
| CSF-1 | Macrophage Colony Stimulating Factor |
| GM-CSF | Granulocyte-Macrophage Colony Stimulating Factor |
| AM phi | Alveolar macrophage |
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| GM-CSF | Anti-granulocyte-macrophage colony-stimulating factor |
| CFU-GM | CFU granulocyte/macrophage |
| CFU-GMs | colony-forming units-granulocyte macrophage |
| CFU-GM | Colony-forming units of granulocyte-macrophage |
| macrophage | Relatively long lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kupffer cells of the liver and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa and tumour cells, release substances that stimulate other cells of the immune system and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans giant cells. (18 Nov 1997) |
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| macrophage activation | The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (maf) and the macrophage migration-inhibitory factor (mmif), immune complexes, c3b, and various peptides, polysaccharides, and immunologic adjuvants. (12 Dec 1998) |
| macrophage colony-stimulating factor | <growth factor> A glycoprotein growth factor that causes the committed cell line to proliferate and mature into macrophages. A cytokine synthesised by mesenchymal cells that stimulates pluripotent stem cells of bone marrow into differentiating towards the production of monocytes (mononuclear phagocytes). The compound stimulates the survival, proliferation, and differentiation of haematopoietic cells of the monocyte-macrophage series. It is a disulfide-bonded glycoprotein dimer with a mw of 70 kD and binds to a single class of high affinity receptor which is identical to the product of the c-fms proto-oncogene. See: colony-stimulating factors. Chemical name: Colony-stimulating factor 1 Acronym: M-CSF (12 Dec 1998) |
| macrophage inflammatory protein | <cytokine> A chemokine that is chemotactic for neutrophils and monocytes, stimulates macrophages, and may play a role in regulating haematopoiesis. Its two variants, mip-1alpha and mip-1beta, are 60% homologous to each other. They are heparin-binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Originally identified as secretory products of macrophages, these chemokines are produced by a variety of cell types including neutrophils, fibroblasts, and epithelial cells. They most likely also play a significant role in respiratory tract defenses. (20 Sep 2002) |
| macrophage inhibition factor | <cytokine> A group of lymphokines (including a 14 kD glycoprotein) produced by activated T lymphocytes that reduces macrophage mobility and probably increases macrophage macrophage adhesion. (18 Nov 1997) |
| macrophage migration inhibition test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| macrophage migration-inhibitory factors | Proteins released by sensitised lymphocytes and possibly other cells that inhibit the migration of macrophages away from the release site. The structure and chemical properties may vary with the species and type of releasing cell. (12 Dec 1998) |
| macrophage-1 antigen | An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b antigen and the beta subunit of the CD18 antigen (antigens, CD18). The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions. (12 Dec 1998) |
| macrophage-activating factor | An agent that stimulates macrophages to attack and ingest cancer cells. They are secreted by stimulated lymphocytes that prime macrophages to become non-specifically cytotoxic to tumours. They also modulate the expression of macrophage cell surface ia antigens. One maf is interferon-gamma (interferon type II). Other factors antigenically distinct from ifn-gamma have also been identified. (12 Dec 1998) |
| macrophages, alveolar | Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. (12 Dec 1998) |
| macrophages, peritoneal | Mononuclear phagocytes derived from bone marrow precursors but resident in the peritoneum. (12 Dec 1998) |
| activated macrophage | A mature macrophage, in an active metabolic state, that is cytotoxic to tumour/target cells, usually following exposure to certain cytokines. Synonym: armed macrophage. (05 Mar 2000) |
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| alveolar macrophage | Macrophage found in lung and that can be obtained by lung lavage, responsible for clearance of inhaled particles and lung surfactant. Metabolism slightly different from peritoneal macrophages (more oxidative metabolism), often have multivesicular bodies that may represent residual undigested lung surfactant. (18 Nov 1997) |
| alveolar macrophage elastase | <enzyme> Metalloproteinase found in human alveolar macrophages Registry number: EC 3.4.24.- Synonym: elastase, alveolar macrophage, metalloproteinase elastase, human macrophage metalloelastase, mmp12 gene product, mmp-12 gene product, mme gene product, macrophage metalloelastase (26 Jun 1999) |
| armed macrophage | A mature macrophage, in an active metabolic state, that is cytotoxic to tumour/target cells, usually following exposure to certain cytokines. Synonym: armed macrophage. (05 Mar 2000) |
| associated macrophage | A mature macrophage in an active metabolic state that is cytotoxic to tumour/target cells, usually following exposure to certain cytokines. (05 Mar 2000) |
| receptors, granulocyte-macrophage colony-stimulating factor | Receptors that bind and internalise the granulocyte-macrophage stimulating factor. Their mw is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor. (12 Dec 1998) |
| receptors, macrophage colony-stimulating factor | Glycoproteins of mw 165 kD which are encoded by the c-fms proto-oncogene. The binding of csf-1 to its receptors activates an intrinsic tyrosine kinase activity resulting in autophosphorylation of the receptors on tyrosine, rapid receptor down-regulation, and phosphorylation of as yet unidentified physiologic substrates that initiate a mitogenic response. (12 Dec 1998) |
| chemotactic factors, macrophage | Cytotaxins liberated from normal or invading cells that specifically attract macrophages. They may be lymphokines, products of antigen, antibody and complement interactions or other. (12 Dec 1998) |
| granulocyte-macrophage colony-stimulating factor | <growth factor, haematology, oncology> An acidic glycoprotein of mw 23 kD with internal disulfide bonds. It is produced in response to a number of inflammatory mediators by mesenchymal cells present in the haemopoietic environment and at peripheral sites of inflammation. It stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from foetal liver progenitor cells. It also has some functional activities in mature granulocytes and macrophages. It is used to promote the recovery of the white blood cells following chemotherapy. Chemical name: Colony-stimulating factor 2 See: colony-stimulating factor. Acronym: GM-CSF (12 Dec 1998) |
| wandering macrophage | <haematology> A macrophage that leaves the blood and migrates to infected tissue. (09 Oct 1997) |
| Hansemann macrophage | Large histiocytes with abundant cytoplasm that may contain Michaelis-Gutmann bodies and one or several nuclei; described in lesions of malacoplakia. (05 Mar 2000) |
| inflammatory macrophage | A macrophage found at sites of inflammation. (05 Mar 2000) |
| fixed macrophage | A relatively immotile macrophage found in connective tissue, lymph nodes, spleen, and bone marrow. Synonym: resting wandering cell. (05 Mar 2000) |
| free macrophage | An actively motile macrophage typically found in sites of inflammation. (05 Mar 2000) |
Synonyms : Activation, Macrophage, Activations, Macrophage, Macrophage Activations
Synonyms : Colony Stimulating Factor 1, Colony Stimulating Factor, Macrophage
Synonyms : Act-2, Act2, BB-10010, LD78, MIP 1, Stem Cell Inhibitor, BB 10010, BB10010, Cell Inhibitor, Stem, Inhibitor, Stem Cell, MIP 1alpha, MIP 1beta, Macrophage Inflammatory Protein 1
Synonyms : Inflammatory Proteins, Macrophage
Synonyms : Macrophage Migration Inhibition Factors, Migration Inhibition Factor, Migration-Inhibitory Factor, Inhibition Factor, Migration, Macrophage Migration Inhibitory Factors, Migration Inhibitory Factor, Migration-Inhibitory Factors, Macrophage
| macrophage |
a large phagocyte; some are fixed and other circulate in the blood stream
출처: wordnet.princeton.edu/perl/webwn
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| macrophage |
A type of phagocyte (cell in the body which 'eats' damaged cells and foreign substances such as virus and bacteria).
출처: www.peteducation.com/dict_alpha_listing.cfm
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| macrophage |
A large immune cell that devours invading pathogens and other intruders. Stimulates other immune cells by presenting them with small pieces of the invader. Macrophages can harbor large quantities of HIV without being killed, acting as reservoirs of the virus.
출처: www.amfar.org/cgi-bin/iowa/bridge.html
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| macrophage |
Large cells found throughout the body, particularly in the spleen, that have the ability to ingest other substances such as "old" red blood cells; also important in the immune response.
출처: www.bdid.com/termsm.htm
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| macrophage |
A "scavenger" white blood cell that engulfs anything recognized as "non-self" (debris, particles, viruses, bacteria, etc.) and destroys it. Macrophages, like CD4 cells, are susceptible to HIV infection.
출처: www.thebody.com/hivnews/aidscare/dec97/pullout.htm...
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| macrophage | a large phagocyte |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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