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| antibiotics, lactam | Compounds containing a four-membered ring with an amide nitrogen and a keto group. This configuration includes bacteriostatic, cell-wall inhibiting antibiotics, such as penicillins and cephalosporins; their analogs and derivatives, such as the penem (or penam) compounds; clavulanic acids; and monobactams. They are substrates for and may act as inhibitors of bacterial beta-lactamases. (12 Dec 1998) |
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| beta-lactam | <pharmacology> A class of broad spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins. (05 Mar 2000) |
| beta-lactam resistance | Nonsusceptibility of an organism to the action of the beta-lactam antibiotics. (12 Dec 1998) |
| lactam | <chemistry> One of a series of anhydrides of an amido type, analogous to the lactones, as oxindol. Origin: Lactone + amido. Source: Websters Dictionary (01 Mar 1998) |
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