| CCK | Chole-Cysto-Kinin |
|---|---|
| CCK-8 | Chole-Cysto-Kinin octapeptide |
| NKA | Neuro-Kinin A |
| KKS | kallikrein-kinin system |
| KKS | Kallikrein-kinin system |
|---|---|
| K-K | kallikrein-kinin |
| kinin | One of a number of widely differing substances having pronounced and dramatic physiological effects. Some (e.g., kallidin and bradykinin) are polypeptides, formed in blood by proteolysis secondary to some pathological process, that stimulate visceral smooth muscle but relax vascular smooth muscle, thus producing vasodilation; others (e.g., kinetin) are plant growth regulators. Origin: G. Kineo, to move, + -in (05 Mar 2000) |
|---|---|
| kinin 9 | <protein> Vasoactive nonapeptide (RPPGFSPFR) formed by action of proteases on kininogens. Very similar to kallidin (which has the same sequence but with an additional N terminal lysine). Bradykinin is a very potent vasodilator and increases permeability of post capillary venules, it acts on endothelial cells to activate phospholipase A2. It is also spasmogenic for some smooth muscle and will cause pain. (18 Nov 1997) |
| kininogen | <biochemistry> Inactive precursor in plasma from which kinin is produced by proteolytic cleavage. (18 Nov 1997) |
| kininogen, high-molecular-weight | A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with prekallikrein. Hmwk is split by plasma kallikrein to produce bradykinin. The complex is a cofactor in the activation of coagulation factor xii. The product of this reaction, xiia, in turn activates prekallikrein to kallikrein. (12 Dec 1998) |
| kininogen, low-molecular-weight | A protein, molecular weight 50 kD, located in various normal tissues. Upon cleavage by kallikrein or other kallikreins, it forms kallidin. Kallidin, in turn, is converted into bradykinin. (12 Dec 1998) |
| kininogenase | <protein> Plasma serine proteases normally present as inactive prekallikreins which are activated by Hageman factor. Act on kininogens to produce kinins. Contain an apple domain. (18 Nov 1997) |
| kininogenin | <protein> Plasma serine proteases normally present as inactive prekallikreins which are activated by Hageman factor. Act on kininogens to produce kinins. Contain an apple domain. (18 Nov 1997) |
| kininogens | <chemical> Endogenous peptides present in most body fluids. Certain enzymes convert them to active kinins which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. High-molecular-weight kininogen (hmwk) is split by plasma kallikrein to produce bradykinin. Low-molecular-weight kininogen (lmwk) is split by tissue kallikrein to produce kallidin. Pharmacological action: cysteine proteinase inhibitors. (12 Dec 1998) |
| kinins | <biochemistry> Inflammatory mediators that cause dilation of blood vessels and altered vascular permeability. Kinins are small peptides produced from kininogen by kallikrein and are broken down by kininases. Act on phospholipase and increase arachidonic acid release and thus prostaglandin (PGE2) production. See: bradykinin, kallidin, C2 kinin. (18 Nov 1997) |
| C2 kinin | <biochemistry, protein> A kinin like fragment generated from complement C2, causes vasodilation and increased vascular permeability. Distinct from bradykinin. (07 Nov 1997) |
|---|---|
| kallikrein-kinin system | A system produced in the distal nephron of the kidney. Its components are kallikrein, kinins, kininase I and II, and enkephalinase. It is involved in mediation and modulation of the renin-angiotensin-aldosterone system, prostaglandins, vasopressins, and in the regulation of sodium-water balance, renal haemodynamics, and particularly blood pressure. The system participates in the control of renal functions and the physiopathology of renal diseases. (12 Dec 1998) |
Synonyms : Fitzgerald Factor, HMWK, High Molecular Weight Kininogen, High Molecular Weight Kininogens, High-Molecular-Weight Kininogens, Kininogens, High Molecular Weight, Kininogen, High Molecular Weight, Kininogens, High-Molecular-Weight
Synonyms : LMWK, Low Molecular Weight Kininogen, Low Molecular Weight Kininogens, Low-Molecular-Weight Kininogens, Kininogen, Low Molecular Weight, Kininogens, Low-Molecular-Weight
Synonyms : Kininogen, Prekinins, Prokinins, T-Kininogen, Thiostatin, Kininogen Cystatins, T Kininogen
Synonyms :
| kinin |
any of a class of plant hormones that promote cell division and delay the senescence of leaves
Ãâó: wordnet.princeton.edu/perl/webwn
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| kinin s. |
the system of proteins involved in the production and destruction of kinins such as bradykinin and kallidin. Kinins are cleaved from precursor substances called kininogens by kallikreins and are rapidly destroyed by kininases. Plasma kallikrein circulates as a proenzyme called prekallikrein and is converted to active form by factor XIIa, which cleaves HMW kininogen, an α2-globulin, to produce bradykinin. Called also kallikrein s.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| kininase |
an enzyme that destroys the activity of circulating kinins.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| kininogen |
either of two plasma α2-globulins that are kinin precursors, called high-molecular-weight k. and low-molecular-weight k.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| kininases, plasma |
Plasma carboxypeptidases that inactivate plasma kinins.
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