| 영문 | steroid | 한글 | 스테로이드 |
|---|---|---|---|
| 설명 | Hydrogenated cyclopentanoperhydrophenanthrene ring system으로 구성된 분자. 생체내에서 중요한 스테로이드는 부신겉질에서 생성되는 스테로이드 호르몬이며 당대사에 관여하는 글루코코르티코이드(glucocorticoid), 염류대사(인체내 존재하는 염분성분(NaCl, KCl, NaOH 등)을 조절하는 대사)에 관여하는 광물코르티코이드(mineralocorticoid), 성호르몬(인체의 성발달에 관여)의 세 가지이다. 스테로이드 호르몬은 부신피질에서 콜레스테롤을 재료로 하여 복잡한 합성단계를 거쳐 합성된다. 글루코코르티코이드는 뇌하수체에서 분비되는 부신겉질자극 호르몬(ACTH)에 의해 생성과 분비가 이루어지나 광물코르티코이드는 레닌-안지오텐신계(신장에서 인체내 염분이 부족시 레닌이 분비되고, 이 자극은 부신으로 전해져 광물코르티코이드인 안지오텐신을 분비하게 됨)의 자극에 의해 분비된다. 글루코코르티코이드는 transcortin과 결합하여 운반되며 반감기는 한시간 정도이나 염류코르티코이드는 대부분이 단백질과 결합하지 않고 유리형으로 남아있어 반감기는 20분에 불과하다. 이들이 간에 도달하면 glucuronic acid에 결합하여 배설된다. |
||
| ACTH | Adreno-Cortico-Tropic(=Tropin)(or steroid) Hormone |
|---|---|
| 3β-HSD | 3β-Hydroxy-Steroid Dehydrogenase |
| 17-KS | 17-Keto-Steroid |
| 17-KS | 17-Keto-Steroid |
| ABCDES | abnormal alignment, bones-periarticular osteoporosis, cartilage-joint space loss, deformities, margi... |
| 3 beta-HSD | 3 beta hydroxy steroid dehydrogenase |
|---|---|
| 3 beta-HSD | 3 beta-hydroxy-steroid dehydrogenase/delta 5-delta 4 isomerase |
| AAS | Anabolic androgenic steroid |
| NSAID | Non Steroid Anti-Inflammatory Drugs |
| SBP | Steroid Binding Protein |
| steroid | A group name for lipids that contain a hydrogenated cyclopentanoperhydrophenanthrene ring system. Some of the substances included in this group are progesterone, adrenocortical hormones, the gonadal hormones, cardiac aglycones, bile acids, sterols (such as cholesterol), toad poisons, saponins and some of the carcinogenic hydrocarbons. (18 Nov 1997) |
|---|---|
| steroid (23R)-hydroxylase | <enzyme> Increased (23r)-hydroxylase activity in patients with cerebrotendinous xanthomatosis, an inborn error of metabolism in bile acid synthesis resulting in (23r)-hydroxylation of bile acids Registry number: EC 1.14.99.- Synonym: bile acid (23r)-hydroxylase, bile alcohol (23r)-hydroxylase (26 Jun 1999) |
| steroid 11 beta-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal tissues. It catalyses the 11-hydroxylation of steroids in the presence of molecular oxygen and consists of an NADPH-specific flavoprotein, a non-haem iron protein, and cytochrome p-450. Its deficiency is a cause of congenital adrenal hyperplasia (adrenal hyperplasia, congenital). Chemical name: Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating) Registry number: EC 1.14.15.4 (12 Dec 1998) |
| steroid 11-alpha-hydroxylase | <enzyme> Converts 11-deoxycortisol to 11-alpha cortisol (the 11-alpha isomer of hydrocortisone) Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 12-monooxygenase | <enzyme> A steroid hydroxylase found in liver microsomes. It catalyses the 12-hydroxylation of steroids in the presence of NADPH, cytochrome p-450, and molecular oxygen. It is an important enzyme in the synthesis of cholic acid from cholesterol in the liver. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating) Registry number: EC 1.14.99.- (12 Dec 1998) |
| steroid 14-alpha-hydroxylase | <enzyme> From induced vegetative cell cultures of mucor piriformis; hydroxylates progesterone to 14-alpha-hydroxyprogesterone in the presence of NADPH and oxygen Registry number: EC 1.14.13.- Synonym: progesterone 14-alpha-hydroxylase (26 Jun 1999) |
| steroid 15-beta-hydroxylase | <enzyme> Contains p-450 and ferredoxin; from bacillus megaterium Registry number: EC 1.14.99.- Synonym: cytochrome p-450 15 beta-hydroxylase, p-450 (15-beta), steroid-15 beta-monooxygenase, cytochrome p-450meg, cytochrome p4502c12, cyp2c12 protein (26 Jun 1999) |
| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
| steroid 19-hydroxylase | <enzyme> Enzyme from adrenal mitochondria; forms 19-hydroxy-11-deoxycorticosterone Registry number: EC 1.14.13.- Synonym: 19-hydroxysteroid hydroxylase, deoxycorticosterone 11-19-hydroxylase (26 Jun 1999) |
| steroid 21-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal cortex microsomes. It catalyses the 21-hydroxylation of corticosteroids and shows a requirement for NADPH and molecular oxygen. Its deficiency is a cause of adrenogenital syndrome. Chemical name: Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) Registry number: EC 1.14.99.10 (12 Dec 1998) |
| steroid 25-hydroxylase | <enzyme> Involved in cholesterol degradation to cholic acid Registry number: EC 1.14.99.- (26 Jun 1999) |
| steroid 5a-reductase | <enzyme> An enzyme that uses NADPH to reduce certain steroids (e.g., the conversion of testosterone to dihydrotestosterone a deficiency of this enzyme is associated with a form of male pseudohermaphroditism in which genetic males have male genitals as well as female external genitalia. (05 Mar 2000) |
| steroid 7 alpha-hydroxylase | <enzyme> Testosterone and androstenedione incubated with microsomes from rat testes produced 7alpha-hydroxytestosterone and 7alpha-hydroxyandrostenedione Registry number: EC 1.14.99.- Synonym: testicular 7 alpha-hydroxylase, 7 alpha-hydroxylase, microsomal 7alpha-hydroxylase, andiostenedione 7 alpha-hydroxylase, sterol 7 alpha-hydroxylase, cytochrome p-450iia1, cytochrome p450iia1 (26 Jun 1999) |
| steroid 9 alpha monooxygenase | <enzyme> Consists of an electron transport chain of NADH-dependent flavoprotein reductase and 2 iron-sulfur proteins; from nocardia Registry number: EC 1.14.99.- Synonym: steroid 9 alpha-hydroxylase (26 Jun 1999) |
| steroid acne | Folliculitis similar to acne vulgaris, but resulting from topical or oral administration of steroids; comedones are rare. (05 Mar 2000) |
| anabolic steroid | <endocrinology> A type of steroid hormone that stimulates the synthesis of protein. Anabolic steroids are compounds which stimulate the body into anabolism. This process involves the building of complex compounds from smaller simpler ones (for example proteins are built from amino acids). This process requires energy. (13 Nov 1997) |
|---|---|
| receptors, steroid | Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behaviour of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. (12 Dec 1998) |
| gonadal steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| saturated steroid 6 alpha-hydroxylase | <enzyme> Acts on 5 alpha-androstane-3 beta,17 beta-diol and 5 alpha-pregnan-3 beta-ol-20-one; does not require cytochrome p-450 Registry number: EC 1.14.99.- Synonym: sat steroid 6alpha-hydroxylase (26 Jun 1999) |
| sex steroid-binding globulin | A protein that transports 65% of the testosterone in plasma. Synonym: sex steroid-binding globulin. (05 Mar 2000) |
| 17-ketogenic steroid assay test | A colourimetric test, based on the Zimmermann reaction, which indicates metabolites or adrenal and testicular steroids excreted as 17-ketones in the urine; increased values are most striking in adrenocortical tumours, decreased values in Addison's disease or in panhypopituitarism. Synonym: ketogenic corticoids test. (05 Mar 2000) |
| 3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase | <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood Registry number: EC 1.1.1.- Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase (26 Jun 1999) |
| 3-oxo-5 beta-steroid delta 4-dehydrogenase | <enzyme> Do not confuse with EC 1.3.1.23 (cholestenone 5 beta-reductase) which is also steroid 5 beta-reductase in chemline; do not use for enzyme using NADP-see EC 1.3.1.23 and EC 1.3.1.3 Chemical name: 3-oxo-5 beta-steroid delta(4)dehydrogenase Registry number: EC 1.3.99.6 Synonym: steroid 5 beta-reductase, testosterone 5 beta-reductase, 4-ene-5 beta-reductase, delta(4)-3-ketosteroid-5 beta-(acceptor)-reductase, testosterone 5beta-reductase, delta(4)-5beta-reductase, cytosolic 4-ene-reductase (26 Jun 1999) |
Synonyms : 11 beta-Hydroxylase, CYP 11B1, Cytochrome P450 11B1, Steroid 11 Hydroxylase, Steroid 11-Hydroxylase, Steroid-11-Hydroxylase, 11 beta Hydroxylase, Cytochrome P 450 CYP11B1, Steroid 11 beta Hydroxylase, Steroid 11 beta Monooxygenase
Synonyms : 12alpha-Hydroxylase, CYP8B1, Cytochrome P450 8B1, Cytochrome P450 CYP8B1, Steroid 12-Hydroxylase, Steroid-12-Hydroxylase, Steroid-12-Monooxygenase, Sterol 12 alpha-Hydroxylase, 12 alpha Hydroxylase, 12 alpha-Hydroxylase, Sterol, 12alpha Hydroxylase
Synonyms : 16-alpha Hydroxylase, 16alpha-Hydroxylase, Estradiol 16-alpha Hydroxylase, Estrogen 16-alpha Hydroxylase, Estrone 16-alpha Hydroxylase, Estrone-3-sulfate 16-alpha Hydroxylase, Progesterone 16 alpha-Hydroxylase, Progesterone 16-alpha-Hydroxylase
Synonyms : 17 alpha-Hydroxylase Cytochrome P-450, 17 alpha-Hydroxyprogesterone Aldolase, 17, 20-Desmolase, Cytochrome P-450(17-alpha), Cytochrome P450(17 alpha), Hydroxyprogesterone Aldolase, Steroid 17 alpha-Hydroxylase, Steroid-17-Hydroxylase, 17 alpha Hydroxylase
Synonyms : 21-Hydroxylase, Cytochrome P-450 21-Hydroxylase, Cytochrome P-450 c21, Cytochrome P-450(c-21), Cytochrome P450c21, Progesterone 21-Hydroxylase, Steroid-21-Hydroxylase, 21 Hydroxylase, Cytochrome P 450 21 Hydroxylase, Cytochrome P 450 CYP21, Cytochrome P 450 c21
| steroidal |
of or relating to steroid hormones or their effects
출처: wordnet.princeton.edu/perl/webwn
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|---|---|
| steroid |
any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects steroid hormone: any hormone affecting the development and growth of sex organs
출처: wordnet.princeton.edu/perl/webwn
|
| steroid hormone |
any hormone affecting the development and growth of sex organs
출처: wordnet.princeton.edu/perl/webwn
|
| steroid |
A type of drug used to relieve swelling and inflammation.
출처: www.stjude.org/glossary
|
| steroid |
Member of a large family of structurally similar lipid substances. Steroid molecules have a basic skeleton consisting of four interconnected carbon rings. Different classes of steroids have different functions. All the natural sex hormones are steroids. Anabolic steroids increase muscle mass. Anti-inflammatory steroids (or corticosteroids) can reduce swelling, pain, and other manifestations of inflammation.
출처: www.amfar.org/cgi-bin/iowa/bridge.html
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| steroid | any hormone affecting the development and growth of sex organs |
|---|---|
| steroid | any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings |
| steroid | any of a group of natural steroid alcohols derived from plants or animals |
| steroid | any hormone affecting the development and growth of sex organs |
| steroid | of or relating to steroid hormones or their effects |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|