| 25-hydroxycholecalciferol | 25-hydroxycholecalciferol (a 3,25-diol);the first step in the biological conversion of vitamin D3 to the more active form, calcitriol; it is more potent than vitamin D3. Synonym: 25-hydroxycholecalciferol, calcifediol. Calcidiol 1a-hydroxylase, 25-hydroxycholecalciferol 1a-hydroxylase, the monooxygenase that forms calcitriol from calcidiol using O2 and NADPH; a deficiency in this enzyme can result in features of a vitamin D deficiency. (05 Mar 2000) |
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| 25-hydroxycholecalciferol 1-hydroxylase | <enzyme> An enzyme that catalyses the formation of 1,25-dihydroxycholecalciferol from 25-hydroxycholecalciferol. The reaction requires oxygen, magnesium, and NAD(p)h. Chemical name: Calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating) Registry number: EC 1.14.13.13 (12 Dec 1998) |
| 25-hydroxycholecalciferol-24-hydroxylase | <enzyme> Cytochrome p-450 monooxygenase system Registry number: EC 1.14.99.- Synonym: 25-hydroxyvitamin d(3)-24-hydroxylase, 25-hydroxyvitamin d(3)-24r-hydroxylase, 25-hc-24-hydroxylase, cytochrome p450cc24, 24-hydroxylase cytochrome p-450, cytochrome p450(24), vitamin d 24-hydroxylase, cyp24 (26 Jun 1999) |
| 25-hydroxycholecalciferol |
the major metabolite synthesized from cholecalciferol (vitamin D3) in the liver and occurring in the serum; it is the precursor of 1,25-dihydroxycholecalciferol. See also table at cholecalciferol. Called also calcifediol, calcidiol, and 25-hydroxyvitamin D3.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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