| hapten | <immunology, molecular biology> Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein). The hapten constitutes a single antigenic determinant, perhaps the best known example is dinitro phenol (DNP) that can be conjugated to BSA and against which antiDNP antibodies are produced (antibodies to the BSA can be adsorbed out). Because the hapten is monovalent, immune complex formation will be blocked if the soluble hapten is present as well as the hapten carrier conjugate (assuming there is more than one hapten per carrier then an immune precipitate can be formed). Competitive inhibition by the soluble small molecule is sometimes referred to as haptenic inhibition and this term has carried over into lectin mediated haemagglutination where monosaccharides are added to try to block haemagglutination: the blocking sugar defines the specificity of the lectin. (18 Nov 1997) |
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| hapten inhibition of precipitation | Inhibition of precipitation that occurs when the precipitin has combined with hapten of the same specificity as the subsequently added antigen. (05 Mar 2000) |
| haptenic inhibition | <immunology, molecular biology> Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein). The hapten constitutes a single antigenic determinant, perhaps the best known example is dinitro phenol (DNP) that can be conjugated to BSA and against which antiDNP antibodies are produced (antibodies to the BSA can be adsorbed out). Because the hapten is monovalent, immune complex formation will be blocked if the soluble hapten is present as well as the hapten carrier conjugate (assuming there is more than one hapten per carrier then an immune precipitate can be formed). Competitive inhibition by the soluble small molecule is sometimes referred to as haptenic inhibition and this term has carried over into lectin mediated haemagglutination where monosaccharides are added to try to block haemagglutination: the blocking sugar defines the specificity of the lectin. (18 Nov 1997) |
| haptens | Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response. (12 Dec 1998) |
| conjugated hapten | A hapten that may cause the production of antibodies when it has been covalently linked to protein. Synonym: conjugated antigen. (05 Mar 2000) |
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| half-hapten | A substance that elicits an antigen-antibody reaction, but no precipitation. (05 Mar 2000) |
| Forssman hapten | A glycolipid from mammalian organs. Compare: Forssman antibody, Forssman antigen. (05 Mar 2000) |
Synonyms : Contact-Sensitizing Agents, Agents, Contact-Sensitizing, Contact Sensitizing Agents
| hapten |
A hapten is a small molecule which can elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one which also does not elicit an immune response by itself. (Generally, only large molecules, infectious agents, or insoluble foreign matter can elicit an immune response in the body). ...
출처: en.wikipedia.org/wiki/Hapten
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| hapten |
A small molecule that is not immunogenic unless attached to a carrier protein.
출처: www.genpromag.com/Glossary~LETTER~H.html
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| hapten |
A substance not inducing antibody formation but able to combine with a specific antibody.
출처: www.hardydiagnostics.com/Glossary-H.html
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| hapten |
A small molecule that cannot initiate an immune response unless first bound to an immunogenic carrier molecule. However, once a response is initiated, a hapten can react specifically with its antibody.
출처: www.sonoma.edu/users/t/thatcher/biol480/voc2.htm
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| hapten inhibition t. |
serologic characterization of an antigenic determinant by employing known haptens to mask the antigen binding site of antibody specific for it.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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