| MGBG | Methylglyoxal bis(guanyl hydrazone |
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| guanyl | The radical of guanine. (05 Mar 2000) |
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| guanyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylate cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylate kinase | <enzyme> Erythrocyte protein p55 is a sequenced membrane-bound guanylate kinase Registry number: EC 2.7.4.8 Synonym: GMP kinase, guanylate kinase 1, erythrocyte protein p55, chapsyn-110, magi-1 protein, maguk enzyme, membrane-associated guanylate kinase (26 Jun 1999) |
| guanylic acid | A major component of ribonucleic acids. Synonym: guanine ribonucleotide, guanosine 5'-monophosphate. Guanylic acid reductase (GMP reductase), an enzyme that catalyses the reaction of GMP with NADPH producing IMP, NH3, and NADP+; a part of the purine salvage pathway. Guanylic acid synthetase (GMP synthetase), an enzyme catalyzing the reaction of l-glutamine, XMP, and ATP to produce GMP, l-glutamate, AMP, and pyrophosphate; a key step in purine biosynthesis. Acronym: GMP (05 Mar 2000) |
| guanylin | <physiology> Peptide occuring in vertebrate gut that elevates the second messenger cyclic GMP in a variety of tissues (including gut) via a membrane guanylate cyclase. The receptor is also the target for the E. Coli heat stable enterotoxin. (18 Nov 1997) |
| guanyloribonuclease | rNase T1. See entries under ribonuclease |
| guanylthiourea | <chemical> 1-amidino-2-thiourea. May protect against hypoxic damage; proposed for treatment of shock due to trauma or blood loss; also stimulates paretic gastrointestinal system. Synonym: guthimine; guthymine. Chemical name: Thiourea, (aminoiminomethyl)- (12 Dec 1998) |
| guanylyl | The radical of guanylic acid. (05 Mar 2000) |
| guanylyl cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
| guanylyl imidodiphosphate | <chemical> 5'-guanylic acid, monoanhydride with imidophosphoric acid. An analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. The nucleotide is a potent stimulator of adenylate cyclase. Synonym: GMP-p(nh)p; gpp(nh)p. Chemical name: 5'-Guanylic acid, monoanhydride with imidodiphosphoric acid (12 Dec 1998) |
| guanylyltransferase | <enzyme> Guanylation of heterologous RNA containing 2 or 3 phosphate or g(5')pppn at their 5' terminal; transfer of a GMP moiety from GTP to the 5' end of an RNA molecule containing at least two terminal phosphate Registry number: EC 2.7.7.- (26 Jun 1999) |
Synonyms : Deoxyguanylate Cyclase, Guanylyl Cyclase, Inosinate Cyclase, Cyclase, Deoxyguanylate, Cyclase, Guanyl, Cyclase, Guanylate, Cyclase, Guanylyl, Cyclase, Inosinate
Synonyms : GCAP Proteins, GCAP1 Protein, GCAP2 Protein, GCAP3 Protein, Guanylate Cyclase-Activating Protein 1, Guanylate Cyclase-Activating Protein 2, Guanylate Cyclase-Activating Protein 3, Guanylyl Cyclase Activating Proteins, Guanylyl Cyclase-Activating Protein 1
Synonyms : ATP-(d)GMP Phosphotransferase, Erythrocyte protein p55, GMP Kinase, Guanosine Monophosphate Kinase, Guanylate Kinase 1, Membrane-Associated Guanylate Kinase, Guanylate Kinase, Membrane-Associated, Kinase 1, Guanylate, Kinase, GMP, Kinase, Guanylate
Synonyms : Guthimine, Guthymine, Gutimin
Synonyms : GMP-P(NH)P, Gpp(NH)p, Guanosine 5'-(Beta, Gamma-Imido)Triphosphate, Guanyl-5'-Imidodiphosphate, P(NH)PPG, Guanyl 5' Imidodiphosphate, Imidodiphosphate, Guanylyl
| guanyl-nucleotide-binding p. |
G p.
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| guanylate |
a dissociated form of guanylic acid.
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| guanylate cyclase |
[EC 4.6.1.2] an enzyme of the lyase class that catalyzes the cyclization of guanosine triphosphate to form cyclic guanosine monophosphate and pyrophosphate.
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| guanylate kinase |
[EC 2.7.4.8] an enzyme of the transferase class that catalyzes the phosphorylation of GMP or dGMP to form the corresponding phosphate compound.
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| guanylic acid |
guanosine monophosphate.
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