| CG | Cardiac glycosides |
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| glycosides | Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (12 Dec 1998) |
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| cardiac glycosides | <chemical> Substances obtained from species of digitalis, strophanthus, and other plants that contain specific steroid glycosides or their semisynthetic derivatives and used in congestive heart failure. They increase the force of cardiac contraction without significantly affecting other parameters, but are very toxic at larger doses. Their mechanism of action usually involves inhibition of the sodium-potassium-exchanging atpase and they are often used in cell biological studies for that purpose. Pharmacological action: anti-arrhythmia agents, cardiotonic agent, enzyme inhibitors. (12 Dec 1998) |
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| purpurea glycosides | The cardioactive precursor glycosides of Digitalis purpurea; they are structurally identical with desacetyl-lanatosides A and B, respectively. See: lanatosides A, B, and C. (05 Mar 2000) |
| digitalis glycosides | <chemical> Glycosides from plants of the genus digitalis. Some of these are useful as cardiotonic and anti-arrhythmia agents. Included also are semi-synthetic derivatives of the naturally occurring glycosides. The term has sometimes been used more broadly to include all cardiac glycosides, but here is restricted to those related to digitalis. Pharmacological action: anti-arrhythmia agents, cardiotonic agent, enzyme inhibitors. (12 Dec 1998) |
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