| GAM | Generalised Additive Models |
|---|---|
| GAD | Generalised Anxiety Disorder |
| GLM | Generalised Linear Model |
| GABEB | Generalised atrophic benign epidermolysis bullosa |
| GCSE | Generalised convulsive status epilepticus |
| generalised | <zoology> Comprising structural characters which are separated in more specialized forms; synthetic; as, a generalised type. Source: Websters Dictionary (01 Mar 1998) |
|---|---|
| generalised anaphylaxis | The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen). See: anaphylactic shock. Synonym: systemic anaphylaxis. (05 Mar 2000) |
| generalised anxiety disorder | Chronic, repeated episodes of anxiety reactions; a psychological disorder in which anxiety or morbid fear and dread accompanied by autonomic changes are prominent features. See: anxiety. (05 Mar 2000) |
| generalised chondromalacia | A degenerative disease of cartilage producing a bizarre form of arthritis, with collapse of the ears, the cartilaginous portion of the nose, and the tracheobronchial tree; death may occur from chronic infection or suffocation because of loss of stability in the tracheobronchial tree of autosomal origin. Synonym: chronic atrophic polychondritis, generalised chondromalacia, Meyenburg's disease, Meyenburg-Altherr-Uehlinger syndrome, relapsing perichondritis, systemic chondromalacia, von Meyenburg's disease. (05 Mar 2000) |
| generalised cortical hyperostosis | <syndrome> An inherited skeletal dysplasia, with mandibular enlargement and thickening of the diaphyses and calvaria, and increased serum alkaline phosphatase; autosomal recessive inheritance. Synonym: generalised cortical hyperostosis. (05 Mar 2000) |
| generalised elastolysis | A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (12 Dec 1998) |
| generalised emphysema | Emphysema affecting all parts of the lobules, in part, or usually the whole, of the lungs, and usually associated with a1-antiprotease deficiency emphysema. Synonym: diffuse emphysema, generalised emphysema, panacinar emphysema. (05 Mar 2000) |
| generalised epidermolytic hyperkeratosis | Diffusely red, eroded skin at birth, with subsequent scaling, tending to improve in later life, characterised by generalised epidermolytic hyperkeratosis and autosomal dominant inheritance. See: epidermolytic hyperkeratosis. Synonym: generalised epidermolytic hyperkeratosis, ichthyismus hystrix, ichthyosis hystrix. (05 Mar 2000) |
| generalised epilepsy | A major category of epilepsy syndromes characterised by one or more types of generalised seizures. (05 Mar 2000) |
| generalised eruptive histiocytoma | A rare recurring generalised eruption in adults of flesh coloured or erythematous papules remaining localised to the skin and consisting of dermal nodules of mononuclear histiocytes that do not stain for lipid. Synonym: nodular non-X histiocytosis. (05 Mar 2000) |
| generalised gangliosidosis | Three forms exist: infantile, generalised; juvenile; and adult; gangliosidosis characterised by accumulation of a specific monosialoganglioside, GM1; due to deficiency of GM1-beta-galactosidase. Synonym: generalised gangliosidosis. (05 Mar 2000) |
| generalised glycogenosis | Glycogenosis due to lysosomal alpha-1,4-glucosidase deficiency, resulting in accumulation of excessive amounts of glycogen of normal chemical structure in heart, muscle, liver, and nervous system. Synonym: generalised glycogenosis, Pompe's disease. (05 Mar 2000) |
| generalised myokymia | Widespread myokymia, present in multiple limbs and often the face; of various causes, including Isaac's syndrome, uraemia, thyrotoxicosis and gold toxicity (gold-myokymia syndrome). (05 Mar 2000) |
| generalised paralysis | Paralysis of both whole sides of the body; survival is usually of short duration. Synonym: generalised paralysis. (05 Mar 2000) |
| generalised pustular psoriasis of Zambusch | An extensive exacerbation of psoriasis, with pustule formation in the normal and psoriatic skin, fever, and granulocytosis; sometimes precipitated by oral steroids. Synonym: generalised pustular psoriasis of Zambusch. A local pustular eruption of the palms and soles, occurring most commonly in a patient with psoriasis; difficult to distinguish from acrodermatitis continua. (05 Mar 2000) |
| persistent generalised lymphadenopathy | A syndrome characterised by reactive hyperplasia of lymph nodes (of at least one month's duration and at two different body sites, not including the inguinal area) in patients infected with the human immunodeficiency virus. The lymph node lesions progress from benign reactive hyperplasia through a stage of mixed follicular hyperplasia, to follicular involution with lymphocyte depletion. Many go on to a malignant non-Hodgkin's lymphoma. (05 Mar 2000) |
|---|---|
| congenital generalised fibromatosis | Multiple subcutaneous and visceral fibrous tumours present at birth; a rare disorder often fatal in the first week of life, although sometimes undergoing spontaneous remission; probable autosomal recessive inheritance. (05 Mar 2000) |
| primary generalised epilepsy | Epilepsy without evidence of focal or multifocal central nervous system disease. Seizures are generalised from onset, both by EEG and clinical criteria. Often a pure genetic form of epilepsy. See: generalised tonic-clonic seizure. (05 Mar 2000) |
| secondarily generalised tonic-clonic seizure | A generalised tonic-clonic seizure that begins with a partial seizure and evolves into a generalised tonic-clonic seizure. (05 Mar 2000) |
| secondary generalised epilepsy | A group of epilepsy syndromes of diverse aetiologies with diffuse or multifocal cerebral involvement. Patients typically have a variety of generalised seizure types, including tonic, atonic, myoclonic, atypical absence, and generalised tonic-clonic seizures. Partial seizures may also occur. One classic syndrome is the Lennox-Gastaut syndrome. Synonym: symptomatic epilepsy. (05 Mar 2000) |
| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
| epilepsy, generalised | Epileptic seizures in which the first clinical changes indicate initial involvement of both hemispheres of the brain, as opposed to epileptic seizures involving a particular focal point of the brain (epilepsy, partial). Generalised seizures can be convulsive or non-convulsive. Consciousness may be impaired and this impairment may be the initial manifestation of the seizure. Motor manifestations, if present, are also bilateral. (12 Dec 1998) |
| generalised | made general |
|---|---|
| generalised | spread throughout a body or system |
| generalised | (biology) not biologically differentiated or adapted to a specific function or environment |
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