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  • insertional mutagen
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EMIC emergency maternal and infant care; Environmental Mutagen Information Center
EMICBACK Environmental Mutagen Information Center Backfile
MUT mutagen
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frameshift mutagen <molecular biology> A mutagen, such as an acridine derivative, that causes a frameshift mutation; codons (base triplets) are read out of phase and different amino acids are made.
(05 Mar 2000)
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 1
mutagen <chemistry, oncology> An agent that can cause an increase in the rate of mutation, includes X-rays, ultraviolet irradiation (260 nm) and various chemicals.
(18 Nov 1997)
intercalating mutagen A mutagen that causes frame-shift mutations by inserting itself between two adjacent bases in a genetic sequence.
(09 Oct 1997)
reading-frameshift mutation <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence.
Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons.
Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation.
(21 Jun 2000)
frameshift <molecular biology> A shift in the reading frame used to translate the base sequence of DNA or mRNA. It is caused by the addition or deletion of one or more of the bases, resulting in an alternative peptide being formed.
(17 Dec 1997)
frameshift mutation <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence.
Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons.
Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation.
(21 Jun 2000)
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