| fibrinogenase | <enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. (18 Nov 1997) |
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| TM-1 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosqamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
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| TM-2 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| TM-3 alpha-fibrinogenase | <enzyme> Isolated from the venom of taiwan habu, trimeresurus mucrosquamatus Registry number: EC 3.4.24.- (26 Jun 1999) |
| fibrinogenase |
thrombin.
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