| disaccharidase deficiency | A digestive disorder caused by the body being unable to produce enough disaccharidase, an enzyme responsible for breaking down carbohydrates in the small intestine. This may cause symptoms such as intestinal gas and diarrhoea. (09 Oct 1997) |
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| disaccharidases | <enzyme> Registry number: EC 3.2.1.- (12 Dec 1998) |
Synonyms :
| disaccharidase |
an enzyme that hydrolyzes disaccharides. In humans, the disaccharidases, comprising the β-glycosidase (lactasephlorhizin hydrolase) complex, sucrase-isomaltase complex; and trehalase, are located in the brush border membrane of the small intestine, hydrolyzing the oligo- and disaccharides produced after luminal digestion of starches and other dietary carbohydrates. See also under deficiency and see disaccharide intolerance, under intolerance.
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| disaccharidase d. |
less than normal activity of disaccharidases of the intestinal mucosa; it usually denotes a generalized deficiency of all such enzymes secondary to a disorder of the small intestine, which clinically may be manifest only as a deficiency of lactase activity, but is sometimes used to denote deficiency of a single enzyme or enzyme complex, e.g., lactase, sucrase-isomaltase complex, or α,α-trehalase. See also individual enzyme deficiencies and see disaccharide intolerance, under intolerance.
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| disaccharidase | an enzyme that catalyzes the hydrolysis of disaccharides into monosaccharides |
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