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  • conformational isomer
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  • conformational map
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SSC single-strand conformational [analysis]; sister strand crossover; somatosensory cortex; standard sal...
SSCP single-stranded conformational polymorphism
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SSCP PCR)-single stand conformational polymorphism
PCR-SSCP Polymerase chain reaction single strand conformational polymorphism
SSCP Single Strand Conformational Polymorphism
SSCP Single Strand Conformational Polymorphism analysis
SSCP Single Stranded Conformational Polymorphism
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CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 2 ÆäÀÌÁö: 1
conformational change <cell biology> Alteration in the shape usually the tertiary structure of a protein as a result of alteration in the environment pH, temperature, ionic strength) or the binding of a ligand (to a receptor) or binding of substrate (to an enzyme).
(18 Nov 1997)
conformational map A graphical representation in which the dihedral angle of rotation about the alpha-carbon to carbonyl-carbon bond in polypeptides is plotted against the dihedral angle of rotation about the alpha-carbon to nitrogen bond.
Synonym: conformational map.
(05 Mar 2000)
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polymorphism, single-stranded conformational Variation occurring within a species in the conformation of denatured DNA fragments. These single-stranded DNA fragments are allowed to partially renature in a way that prevents the formation of double-stranded DNA. The fragments are run on polyacrylamide gels under various conditions to detect subtle changes in migration due to altered secondary structure. The resulting bands will align themselves if the fragments are the same, but will misalign if any point mutations are present. Sscps have been used in detecting mutations in various genes, such as oncogenes, tumour suppressor genes, and genes responsible for genetic diseases.
(12 Dec 1998)
Haworth conformational formula <biochemistry> Of cyclic sugars, for the pyranoses, these depict those shapes (conformations) on which none, one, or two ring-atoms lie outside the plane of the ring.
If there are two such atoms para to each other, they can lie 1) on opposite sides of the plane (trans), giving chair forms, or 2) on the same side of the plane (cis), giving boat forms. For beta-d-ribopyranose, the two chair forms (4C1 and 1C4) are depicted.
Similarly, there are six boat conformations. If the two (trans) exoplanar atoms are meta to each other, the conformation is a skew form; if the two atoms are ortho to each other, the conformation is a half-chair form.
For the furanoses, the envelope conformations have one ring-atom exoplanar. If there are three adjacent, coplanar ring-atoms (the two exoplanar ring-atoms on opposite sides of the plane), the conformations are twist forms.
(05 Mar 2000)
single stranded conformational polymorphism Technique for detecting point mutations in genes by amplifying a region of genomic DNA (using asymmetric PCR) and running the resulting product on a high quality gel. Single base substitutions can alter the secondary structure of the fragment in the gel, producing a visible shift in its mobility.
(18 Nov 1997)
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conformational i. the relationship between stereoisomers that differ only by rotations about single bonds (conformers).
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conformational entropy calculated from the probability that a state could be reached by chance alone
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