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POMC Pro-Opio-Melano-Cortin
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cortin <drug, endocrinology, pharmacology> Any of the steroids elaborated by the adrenal cortex (excluding the sex hormones of adrenal origin) in response to the release of adrenocorticotrophin or adrenocorticotropic hormone (ACTH) by the pituitary gland, to any of the synthetic equivalents of these steroids or to angiotensin II.
They are divided, according to their predominant biological activity, into three major groups: glucocorticoids (e.g. Cortisol, cortisone), chiefly influencing carbohydrate, fat and protein metabolism, mineralocorticoids (for example aldosterone), affecting the regulation of electrolyte and water balance and C19 androgens.
Some corticosteroids exhibit both types of activity in varying degrees and others exert only one type of effect.
The corticosteroids are used clinically for hormonal replacement therapy, for suppression of ACTH secretion by the anterior pituitary, as antineoplastic, antiallergic and anti-inflammatory agents and to suppress the immune response.
Synonym: adrenocortical hormone, corticoid.
(13 Nov 1997)
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Cortinariaceae a family of fungi belonging to the order Agaricales
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Cortinarius the largest genus in the Agaricales; agarics having rusty spores and prominent cortinae (cobwebby partial veils)
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cortin a cobwebby partial veil consisting of silky fibrils
cortin a family of fungi belonging to the order Agaricales
cortin the largest genus in th Agaricales
cortin a fungus with large tawny caps and pale cinnamon gills and a red band of veil around the stalk
cortin an edible fungus with a slimy viscid cap that is initially yellow but turns olive and then tawny
cortin a fungus with a viscid wrinkled tawny cap
cortin a poisonous fungus with a bright yellow brown cap and a long cinnamon colored stalk
cortin a fungus with a reddish purple cap having a smooth slimy surface
cortin a fungus with a dry brown cap and rusty red gills and a yellowish stalk
cortin a fungus with a sticky lavender cap and stalk that whitish above and covered with a silky lavender sheath
cortin a fungus that is violet over-all with a squamulose cap
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